CD62E antibody | CL2/6
Mouse anti Human CD62E:Biotin
Mouse anti Human CD62E:FITC
Mouse anti Human CD62E
- Product Type
- Monoclonal Antibody
- Clone
- CL2/6
- Isotype
- IgG2a
Product Code | Applications | Pack Size | List Price | Quantity |
---|---|---|---|---|
MCA1969B | F | 100 Tests |
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MCA1969F | F | 100 Tests |
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MCA1969 | C F IF | 0.1 mg |
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Mouse anti Human CD62E antibody, clone CL2/6 has been shown to inhibit the binding of human neutrophils to stimulated HUVECS.
Product Details
- Target Species
- Human
- Product Form
- Purified IgG conjugated to Biotin - liquid
- Product Form
- Purified IgG conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC) - liquid
- Product Form
- Purified IgG - liquid
- Buffer Solution
- TRIS buffered saline
- Buffer Solution
- TRIS buffered saline
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
0.02% Sodium Azide 1% Bovine Serum Albumin - Preservative Stabilisers
0.02% Sodium Azide 1% Bovine Serum Albumin - Preservative Stabilisers
0.09% Sodium Azide - Approx. Protein Concentrations
- IgG concentration 1.0mg/ml
Storage Information
- Storage
- Store at +4oC or at -20oC if preferred.
This product should be stored undiluted.
Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. - Storage
- Store at +4oC or at -20oC if preferred.
This product should be stored undiluted.
Storage in frost free freezers is not recommended. This product is photosensitive and should be protected from light.
Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. - Storage
- Store at +4oC or at -20oC if preferred.
This product should be stored undiluted.
Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. - Guarantee
- 18 months from date of despatch.
- Guarantee
- 18 months from date of despatch.
- Guarantee
- 18 months from date of despatch.
More Information
- UniProt
- P16581 Related reagents
- Entrez Gene
- SELE Related reagents
- GO Terms
- GO:0007157 heterophilic cell-cell adhesion
- GO:0002092 positive regulation of receptor internalization
- GO:0002523 leukocyte migration involved in inflammatory response
- GO:0016021 integral to membrane
- GO:0004888 transmembrane receptor activity
- GO:0005615 extracellular space
- GO:0005901 caveola
- GO:0005905 coated pit
- GO:0007202 activation of phospholipase C activity
- GO:0019722 calcium-mediated signaling
- GO:0030029 actin filament-based process
- GO:0030863 cortical cytoskeleton
- GO:0032496 response to lipopolysaccharide
- GO:0033691 sialic acid binding
- GO:0034612 response to tumor necrosis factor
- GO:0043274 phospholipase binding
- GO:0048471 perinuclear region of cytoplasm
- GO:0050727 regulation of inflammatory response
- GO:0050901 leukocyte tethering or rolling
- GO:0070492 oligosaccharide binding
- GO:0070555 response to interleukin-1
- Regulatory
- For research purposes only
Applications of CD62E antibody
Application Name | Verified | Min Dilution | Max Dilution |
---|---|---|---|
Flow Cytometry | |||
Flow Cytometry | |||
Flow Cytometry | 1/20 | ||
Immunofluorescence | |||
Immunohistology - Frozen | 0.5ug/ml | 2.0ug/ml |
- Flow Cytometry
- Use 10ul of the suggested working dilution to label 106 cells in 100ul.
- Flow Cytometry
- Use 10ul of the suggested working dilution to label 106 cells in 100ul.
- Flow Cytometry
- Use 10ul of the suggested working dilution to label 106 cells in 100ul.
Secondary Antibodies Available
Negative Isotype Controls Available
Description | Product Code | Applications | Pack Size | List Price | Quantity |
---|---|---|---|---|---|
Mouse IgG2a Negative Control:FITC | MCA929F | F | 100 Tests |
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Mouse IgG2a Negative Control | MCA929 | F | 100 Tests |
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Useful Reagents Available
Description | Product Code | Applications | Pack Size | List Price | Quantity |
---|---|---|---|---|---|
Human Seroblock | BUF070A | F | 50 Test | ||
Human Seroblock | BUF070B | F | 200 Test | ||
Human Seroblock | BUF070A | F | 50 Test | ||
Human Seroblock | BUF070B | F | 200 Test |
Product Specific References
References for CD62E antibody
-
Abbassi, O. et al. (1993) E-selectin supports neutrophil rolling in vitro under conditions of flow.
J Clin Invest. 92 (6): 2719-30. -
Kishimoto, T.K. et al. (1991) Antibodies against human neutrophil LECAM-1 (LAM-1/Leu-8/DREG-56 antigen) and endothelial cell ELAM-1 inhibit a common CD18-independent adhesion pathway in vitro.
Blood. 78: 805-11. -
Marin, C. et al. (2011) Mediterranean diet reduces endothelial damage and improves the regenerative capacity of endothelium.
Am J Clin Nutr. 93: 267-74. -
Rius, C. et al. (2010) Trans- but not cis-resveratrol impairs angiotensin-II-mediated vascular inflammation through inhibition of NF-κB activation and peroxisome proliferator-activated receptor-gamma upregulation.
J Immunol. 185: 3718-27. -
Wassmer, S.C. et al. (2011) Vascular endothelial cells cultured from patients with cerebral or uncomplicated malaria exhibit differential reactivity to TNF.
Cell Microbiol. 13: 198-209. -
Nieuwland, R. et al. (2000) Cellular origin and procoagulant properties of microparticles in meningococcal sepsis.
Blood. 95: 930-5. -
Lo. C. Y. et al. (2013) The use of surface immobilization of P-selectin glycoprotein ligand-1 on mesenchymal stem cells to facilitate selectin mediated cell tethering and rolling
Biomaterials. 34 (33): 8213-22.