CD56 antibody | ERIC-1
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Mouse anti Human CD56
- Product Type
- Monoclonal Antibody
- Clone
- ERIC-1
- Isotype
- IgG1
- Specificity
- CD56
Antibody Quality and Performance Guarantee
| Mouse anti Human CD56 antibody, clone ERIC-1 recognizes N-CAM expressed on developing and adult neuroectodermal tissues in humans. Neuroectodermal tumours also stain including Glioma, ependymoma, neuroblastoma, medulloblastoma, retinoblastoma and teratoma. Oat cell carcinoma and Wilms tumour are also highly reactive. Mouse anti Human CD56 antibody, clone ERIC-1 will react on Natural Killer cells and recognizes 140, 180 and 120 kDa NCAM isoforms. |
- Target Species
- Human
- Product Form
- Purified IgG - liquid
- Preparation
- Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant.
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- <0.1% Sodium Azide (NaN3)
- Immunogen
- Human retinoblastoma tumour cells.
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
- Fusion Partners
- Spleen cells from immunised BALB/c mice were fused with cells of the P3/X63.Ag8 mouse myeloma line.
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| ELISA |  |
80ng/ml | |
| Flow Cytometry | |||
| Immunoblotting | |
||
| Immunohistology - Frozen | |
1/50 | 1/100 |
Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
- Histology Positive Control Tissue
- Neuroblastoma
References for CD56 antibody
-
Bourne, S. P. et al. (1990) A monoclonal antibody (ERIC-1), raised against retinoblastoma, that recognizes the neural cell adhesion molecule (NCAM) expressed on brain and tumours arising from the neuroectoderm
J. Neuro-Oncology. 10: 111-9. -
Whitworth, M.K. et al. (2007) Cervical leukocyte sub-populations in idiopathic preterm labour.
J Reprod Immunol. 75: 48-55. -
Salvatore, G. et al. (2015) Human monocyte-derived dendritic cells turn into foamy dendritic cells with IL-17A.
J Lipid Res. 56 (6): 1110-22. -
Preuße, C. et al. (2012) Immune-mediated necrotizing myopathy is characterized by a specific Th1-M1 polarized immune profile.
Am J Pathol. 181 (6): 2161-71. -
Quenby, S. et al. (2005) Prednisolone reduces preconceptual endometrial natural killer cells in women with recurrent miscarriage.
Fertil Steril. 84 (4): 980-4. -
Debeer, S. et al. (2013) Comparative histology and immunohistochemistry of porcine versus human skin.
Eur J Dermatol. 23 (4): 456-66. -
Criel, A. et al. (1997) Further characterization of morphologically defined typical and atypical CLL: a clinical, immunophenotypic, cytogenetic and prognostic study on 390 cases.
Br J Haematol. 97 (2): 383-91. -
Cameron, A.L. et al. (2002) Natural killer and natural killer-T cells in psoriasis.
Arch Dermatol Res. 294 (8): 363-9.
View The Latest Product References
-
McIntosh K et al. (2006) The immunogenicity of human adipose-derived cells: temporal changes in vitro.
Stem Cells. 24 (5): 1246-53. -
Allenbach, Y. et al. (2016) Dermatomyositis With or Without Anti-Melanoma Differentiation-Associated Gene 5 Antibodies: Common Interferon Signature but Distinct NOS2 Expression.
Am J Pathol. 186 (3): 691-700. -
Meinhardt, J. et al. (2021) Olfactory transmucosal SARS-CoV-2 invasion as a port of central nervous system entry in individuals with COVID-19.
Nat Neurosci. 24 (2): 168-75. -
Preuße, C. et al. (2016) Differential roles of hypoxia and innate immunity in juvenile and adult dermatomyositis.
Acta Neuropathol Commun. 4 (1): 45. -
Siegert, E. et al. (2021) Systemic sclerosis-associated myositis features minimal inflammation and characteristic capillary pathology.
Acta Neuropathol. 141 (6): 917-27.
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