CD24 antibody | SN3
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F ResetMouse anti Human CD24
- Product Type
- Monoclonal Antibody
- Clone
- SN3
- Isotype
- IgG1
- Specificity
- CD24
Antibody Quality and Performance Guarantee
| Mouse anti Human CD24 antibody, clone SN3 recognizes the human CD24 cell surface antigen, a heavily glycosylated molecule of ~35-45 kDa. CD24 is expressed by granulocytes and B lymphocytes, and by some activated T cells and T cell malignancies. |
- Target Species
- Human
- Species Cross-Reactivity
-
Target Species Cross Reactivity Chimpanzee - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Preparation
- Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% sodium azide (NaN3)
- Carrier Free
- Yes
- Immunogen
- Glycoproteins purified from human NALM-1 cell line
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
- Fusion Partners
- Spleen cells from immunized BALB/c mice were fused with cells of a mouse myeloma cell line
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Flow Cytometry |  |
1/50 | 1/100 |
| Immunohistology - Frozen 1 | |
||
| Immunohistology - Paraffin |
- 1The epitope recognised by this antibody is reported to be sensitive to formaldehyde fixation and tissue processing. Bio-Rad recommends the use of acetone fixation for frozen sections.
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
- Flow Cytometry
- Use 10μl of the suggested working dilution to label 106 cells or 100μl whole blood
- Histology Positive Control Tissue
- Tonsil
| Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
|---|---|---|---|---|---|---|---|
| Mouse IgG1 Negative Control | MCA928 | F | 100 Tests |
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Log in | ||
| List Price | Your Price | ||||||
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| Description | Mouse IgG1 Negative Control | ||||||
Source Reference
-
Barcos, M. et al. (1986) Follicular mantle zone cell subpopulations detected by monoclonal antibody SN3.
Hematol Oncol. 4 (4): 251-9.
References for CD24 antibody
-
Fukukawa, T. et al. (1986) New monoclonal antibodies SN3, SN3a, and SN3b directed to sialic acid of glycoprotein on human non-T leukemia cells.
Exp Hematol. 14 (9): 850-5. -
Ohyama, M. et al. (2006) Characterization and isolation of stem cell-enriched human hair follicle bulge cells.
J Clin Invest. 116:249-60. -
Kap, Y.S. et al. (2009) A monoclonal antibody selection for immunohistochemical examination of lymphoid tissues from non-human primates.
J Histochem Cytochem. 57 (12): 1159-67. -
Sallustio, F. et al. (2010) TLR2 plays a role in the activation of human resident renal stem/progenitor cells.
FASEB J. 24 (2): 514-25. -
Kanderová, V. et al. (2010) Aberrantly expressed CEACAM6 is involved in the signaling leading to apoptosis of acute lymphoblastic leukemia cells.
Exp Hematol. 38: 653-660.e1. -
Franz, C. et al. (2016) Extracellular vesicles in human follicular fluid do not promote coagulation.
Reprod Biomed Online. 33 (5): 652-5.
- RRID
- AB_321526
- UniProt
- P25063
- Entrez Gene
- CD24
- GO Terms
- GO:0005886 plasma membrane
- GO:0001666 response to hypoxia
- GO:0001775 cell activation
- GO:0001959 regulation of cytokine-mediated signaling pathway
- GO:0002237 response to molecule of bacterial origin
- GO:0002768 immune response-regulating cell surface receptor signaling pathway
- GO:0004871 signal transducer activity
- GO:0016055 Wnt receptor signaling pathway
- GO:0007204 elevation of cytosolic calcium ion concentration
- View More GO Terms
- GO:0007411 axon guidance
- GO:0008629 induction of apoptosis by intracellular signals
- GO:0009986 cell surface
- GO:0031225 anchored to membrane
- GO:0016337 cell-cell adhesion
- GO:0016477 cell migration
- GO:0019901 protein kinase binding
- GO:0030296 protein tyrosine kinase activator activity
- GO:0030856 regulation of epithelial cell differentiation
- GO:0031295 T cell costimulation
- GO:0032597 B cell receptor transport into membrane raft
- GO:0032600 chemokine receptor transport out of membrane raft
- GO:0032913 negative regulation of transforming growth factor-beta3 production
- GO:0042104 positive regulation of activated T cell proliferation
- GO:0042632 cholesterol homeostasis
- GO:0043406 positive regulation of MAP kinase activity
- GO:0043408 regulation of MAPKKK cascade
- GO:0043627 response to estrogen stimulus
- GO:0045121 membrane raft
- GO:0045730 respiratory burst
View more products with CD24 specificity
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