CD121a antibody | 35730 (49/20)
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Mouse anti human CD121a, clone 35730, recognizes interleukin-1 receptor type 1 (IL1R1). IL1RA/CD121a is widely expressed in a number of cell types including T cells and fibroblasts (Sims et al.)and is involved in the activation of NF-kappa-B (Slack et al.).
Product Details
- Target Species
- Human
- Product Form
- Purified IgG - liquid
- Preparation
- Purified IgG prepared by affinity chromatography from ascites
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- <5% Trehalose
- Immunogen
- Recombinant peptide corresponding to the extracellular domain of human CD121a expressed in insect cell line Sf21.
- Approx. Protein Concentrations
- IgG concentration 0.5 mg/ml
Storage Information
- Storage
- Store at -20°C only.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. - Guarantee
- 12 months from date of despatch
More Information
- UniProt
- P14778
- Entrez Gene
- IL1R1
- GO Terms
- GO:0004909 interleukin-1, Type I, activating receptor activity
- GO:0005887 integral to plasma membrane
- GO:0005161 platelet-derived growth factor receptor binding
- GO:0045087 innate immune response
- GO:0070498 interleukin-1-mediated signaling pathway
- GO:0070555 response to interleukin-1
- Regulatory
- For research purposes only
Applications of CD121a antibody
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| ELISA | |||
| Western Blotting |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using the appropriate negative/positive controls.
Copyright © 2021 Bio-Rad Antibodies (formerly AbD Serotec)
Secondary Antibodies Available
Product Specific References
Further Reading
-
Sims, J. et al. (1989) Cloning the interleukin 1 receptor from human T cells.
Proc Natl Acad Sci U S A. 86: 8946-50. -
Slack, J. et al. (2000) Identification of two major sites in the type I interleukin-1 receptor cytoplasmic region responsible for coupling to pro-inflammatory signaling pathways.
J Biol Chem. 275:4670-8.
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