CCL8 antibody | E07-8G5
Mouse anti Human CCL8
- Product Type
- Monoclonal Antibody
- Clone
- E07-8G5
- Isotype
- IgG2a
- Specificity
- CCL8
| Mouse anti Human CCL8 antibody, clone E07-8G5, recognizes C-C motif chemokine-8 (CCL8) also known as HC14, monocyte chemoattractant protein 2, monocytes chemotactic protein 2 and small-inducible cytokine A8. CCL8 is a member of the C-C chemokine subfamily and is an agonist for C-C chemokine receptor type 2 and CCR5 (Ge et al. 2017). Through these receptors, CCL8 is involved in the immune response by attracting monocytes, T-lymphocytes, natural killer cells, basophils, mast cells and eosinophils (Farmaki et al. 2020). Proteolytic cleavage of CCL8 to CCL8 (6-76) converts the chemokine into a potent inhibitor of C-C chemokine-induced chemotaxis (Proost et al. 1998). The purified Mouse anti Human CCL8 antibody, clone E07-8G5 (MCA6266GA) can be used as a capture antibody in a sandwich ELISA with the biotinylated Mouse anti Human CCL8 antibody, clone E09-8A1 (MCA6267B) as the detection antibody. |
- Target Species
- Human
- Product Form
- Purified IgG - liquid
- Preparation
- Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3)
- Carrier Free
- Yes
- Immunogen
- E. coli derived recombinant human full length CCL8 (Gln24-Pro99)
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
- Fusion Partners
- Cell fusion between immunized BALB/c mouse spleen cells and mouse myeloma SP2/0
- ELISA Matched Pair(s)
-
ELISA Matched Pair-Detection Antibody:
MCA6267B
ELISA Antigen-Positive Control:
PHP297
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| ELISA |  |
1.0 ug/ml |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
| Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
|---|---|---|---|---|---|---|---|
| Mouse anti Human CCL8:Biotin | MCA6267B | E | 0.1 mg |
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| List Price | Your Price | ||||||
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| Description | Mouse anti Human CCL8:Biotin | ||||||
| Recombinant Human CCL8 | PHP297 | E | 10 µg | Log in | |||
| List Price | Your Price | ||||||
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| Description | Recombinant Human CCL8 | ||||||
- Synonyms
- MCP-2
- UniProt
- P80075
- Entrez Gene
- CCL8
- GO Terms
- GO:0009615 response to virus
- GO:0004871 signal transducer activity
- GO:0005615 extracellular space
- GO:0006816 calcium ion transport
- GO:0006887 exocytosis
- GO:0006935 chemotaxis
- GO:0006954 inflammatory response
- GO:0006955 immune response
- GO:0007267 cell-cell signaling
- View More GO Terms
- GO:0008009 chemokine activity
- GO:0008201 heparin binding
MCA6266GA
100005395
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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