Mouse anti Human CCL14 antibody, clone B12-1D8,
recognizes C-C motif chemokine 14, also known as HCC1 and NCC-2. CCL14 is a CC-type chemokine which is constitutively expressed in many tissues (Gu et al. 2020
), and present at very high concentrations in normal human plasma (Savino et al. 2009
). This chemokine is involved with activation of immune cells, promoting chemotaxis of monocytes, eosinophils, and T lymphoblasts. CCL14 is involved with pathogenesis of allergic airway inflammation and some cancers. It has been identified as a prognostic biomarker in hepatocellular carcinoma, where it modules the cell cycle and promotes apoptosis (Zhu et al. 2019
This purified Mouse anti Human CCL14 antibody, clone B12-1D8 (MCA6178GA) can be used as a capture antibody in a sandwich ELISA with the biotinylated Mouse anti Human CCL14 antibody, clone B02-1G7 (MCA6179B
) as the detection antibody.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Applications of CCL14 antibody
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.