C6 antibody | 056B-184.108.40.206
Mouse anti Human C6
- Product Type
- Monoclonal Antibody
|Mouse anti Human C6 antibody, clone 056B-220.127.116.11 recognises complement component 6 (C6), a 104 kDa member of the complement C6/C7/C8/C9 family present in blood serum. The factor I modules of C6 bind the C-terminus of the C5b alpha-chain, anchoring the molecule to the membrane; they also binds complement component 7. This enables the formation of the C5b–7 precursor complex. C5b–7 then functions as a receptor for components C8 and C9 which form the complement membrane attack complex (MAC). Deficiency of C6 results in susceptibility to bacterial infection.
Mouse anti Human C6 antibody, clone 056B-18.104.22.168 recognises C6 as a component of the MAC.
- Target Species
- Product Form
- Purified IgG - liquid
- Purified IgG prepared by affinity chromatography on Protein A from ascites
- Buffer Solution
- Borate buffered saline
- Preservative Stabilisers
- 0.1% Sodium Azide (NaN3)
- Purified human C6.
- Approx. Protein Concentrations
- Current, batch-specific concentration 1.0 mg/ml
- For research purposes only
- Guaranteed until date of expiry. Please see product label.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
|Application Name||Verified||Min Dilution||Max Dilution|
|Immunohistology - Frozen|
- Histology Positive Control Tissue
- Kidney from post streptococcal glomerulonephritis patients
|Description||Product Code||Applications||Pack Size||List Price||Your Price||Quantity|
|Mouse IgG1 Negative Control||MCA928||F||100 Tests||Log in|
|List Price||Your Price|
|Description||Mouse IgG1 Negative Control|
References for C6 antibody
DiScipio, R.G. et al. (1999) Function of the factor I modules (FIMS) of human complement component C6.
J Biol Chem. 274 (45): 31811-8.
- Complement Component 6
- Entrez Gene
- GO Terms
- GO:0005515 protein binding
- GO:0005579 membrane attack complex
- GO:0006958 complement activation, classical pathway
- GO:0019835 cytolysis
- GO:0045087 innate immune response
MCA2666159918 170508 171204
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"View all Anti-Human Products
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