C6 antibody | 056B-214.2.4.2

Mouse anti Human C6
- Product Type
- Monoclonal Antibody
- Clone
- 056B-214.2.4.2
- Isotype
- IgG1
- Specificity
- C6
Mouse anti Human C6 antibody, clone 056B-214.2.4.2 recognises complement component 6 (C6), a 104 kDa member of the complement C6/C7/C8/C9 family present in blood serum. The factor I modules of C6 bind the C-terminus of the C5b alpha-chain, anchoring the molecule to the membrane; they also binds complement component 7. This enables the formation of the C5b–7 precursor complex. C5b–7 then functions as a receptor for components C8 and C9 which form the complement membrane attack complex (MAC). Deficiency of C6 results in susceptibility to bacterial infection. Mouse anti Human C6 antibody, clone 056B-214.2.4.2 recognises C6 as a component of the MAC. |
- Target Species
- Human
- Product Form
- Purified IgG - liquid
- Preparation
- Purified IgG prepared by affinity chromatography on Protein A from ascites
- Buffer Solution
- Borate buffered saline
- Preservative Stabilisers
- 0.1% Sodium Azide (NaN3)
- Immunogen
- Purified human C6.
- Approx. Protein Concentrations
- Current, batch-specific concentration 1.0 mg/ml
- Regulatory
- For research purposes only
- Guarantee
- Guaranteed until date of expiry. Please see product label.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
Application Name | Verified | Min Dilution | Max Dilution |
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ELISA | ![]() |
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Flow Cytometry | ![]() |
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Immunohistology - Frozen | ![]() |
- Histology Positive Control Tissue
- Kidney from post streptococcal glomerulonephritis patients
Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
---|---|---|---|---|---|---|---|
Mouse IgG1 Negative Control | MCA928 | F | 100 Tests |
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List Price | Your Price | ||||||
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Description | Mouse IgG1 Negative Control |
References for C6 antibody
-
DiScipio, R.G. et al. (1999) Function of the factor I modules (FIMS) of human complement component C6.
J Biol Chem. 274 (45): 31811-8.
- Synonyms
- Complement Component 6
- RRID
- AB_2067310
- UniProt
- P13671
- Entrez Gene
- C6
- GO Terms
- GO:0005515 protein binding
- GO:0005579 membrane attack complex
- GO:0006958 complement activation, classical pathway
- GO:0019835 cytolysis
- GO:0045087 innate immune response
MCA2666



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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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