C6 antibody | 056B-18.104.22.168
|Mouse anti Human C6 antibody, clone 056B-22.214.171.124 recognises complement component 6 (C6), a 104 kDa member of the complement C6/C7/C8/C9 family present in blood serum. The factor I modules of C6 bind the C-terminus of the C5b alpha-chain, anchoring the molecule to the membrane; they also binds complement component 7. This enables the formation of the C5b–7 precursor complex. C5b–7 then functions as a receptor for components C8 and C9 which form the complement membrane attack complex (MAC). Deficiency of C6 results in susceptibility to bacterial infection.
Mouse anti Human C6 antibody, clone 056B-126.96.36.199 recognises C6 as a component of the MAC.
- Target Species
- Product Form
- Purified IgG - liquid
- Purified IgG prepared by affinity chromatography on Protein A from ascites
- Buffer Solution
- Borate buffered saline
- Preservative Stabilisers
- 0.1% Sodium Azide (NaN3)
- Purified human C6.
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
- For research purposes only
- Guaranteed until date of expiry. Please see product label.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
|Application Name||Verified||Min Dilution||Max Dilution|
|Immunohistology - Frozen|
- Histology Positive Control Tissue
- Kidney from post streptococcal glomerulonephritis patients
References for C6 antibody
DiScipio, R.G. et al. (1999) Function of the factor I modules (FIMS) of human complement component C6.
J Biol Chem. 274 (45): 31811-8.
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