Mouse anti C-peptide antibody, clone C-PEP-01 recognizes human C-peptide (also known as connecting peptide) a peptide released when proinsulin is cleaved to produce insulin. It can also be used to detect proinsulin.
- Target Species
- Product Form
- Purified IgG - liquid
- Purified IgG prepared by sequential precipitation with caprylic acid and ammonium sulphate.
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- Human C-peptide conjugated to BSA.
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
- This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
- 12 months from date of despatch
- Entrez Gene
- GO Terms
negative regulation of acute inflammatory response
insulin receptor binding
insulin-like growth factor receptor binding
endoplasmic reticulum lumen
glucose metabolic process
energy reserve metabolic process
regulation of cellular amino acid metabolic process
G-protein coupled receptor protein signaling pathway
regulation of insulin secretion
positive regulation of cell proliferation
insulin receptor signaling pathway
fibroblast growth factor receptor signaling pathway
positive regulation of vasodilation
positive regulation of phosphatidylinositol 3-kinase cascade
positive regulation of glucose import
positive regulation of lipid biosynthetic process
regulation of transmembrane transporter activity
positive regulation of cell growth
positive regulation of cell migration
endocrine pancreas development
positive regulation of protein autophosphorylation
activation of protein kinase B activity
regulation of gene-specific transcription
negative regulation of NAD(P)H oxidase activity
negative regulation of protein catabolic process
negative regulation of apoptosis
positive regulation of MAPKKK cascade
positive regulation of nitric oxide biosynthetic process
positive regulation of cell differentiation
negative regulation of gluconeogenesis
positive regulation of glycogen biosynthetic process
positive regulation of DNA replication
negative regulation of glycogen catabolic process
positive regulation of glycolysis
positive regulation of mitosis
negative regulation of proteolysis
negative regulation of vasodilation
negative regulation of fatty acid metabolic process
positive regulation of insulin receptor signaling pathway
alpha-beta T cell activation
negative regulation of protein secretion
positive regulation of cytokine secretion
positive regulation of peptidyl-tyrosine phosphorylation
negative regulation of lipid catabolic process
positive regulation of nitric-oxide synthase activity
positive regulation of NF-kappaB transcription factor activity
positive regulation of protein kinase B signaling cascade
fatty acid homeostasis
negative regulation of respiratory burst involved in inflammatory response
positive regulation of respiratory burst
- For research purposes only
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Applications of C-Peptide antibody
|Immunohistology - Frozen
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using the appropriate negative/positive controls.
Copyright © 2021 Bio-Rad Antibodies (formerly AbD Serotec)
Secondary Antibodies Available
Product Specific References
References for C-Peptide antibody
Hilgert, I. et al. (1991) A monoclonal antibody applicable for determination of C-peptide of human proinsulin by RIA.
Hybridoma. 10: 379-86.
Afrikanova, I. et al. (2011) Inhibitors of Src and focal adhesion kinase promote endocrine specification: impact on the derivation of β-cells from human pluripotent stem cells.
J Biol Chem. 286 (41): 36042-52.
Vasic, D. & Walcher, D. (2012) C-peptide: a new mediator of atherosclerosis in diabetes.
Mediators Inflamm. 2012: 858692.
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