C-Peptide antibody | C-PEP-01
Mouse anti Human C-Peptide
- Product Type
- Monoclonal Antibody
- Clone
- C-PEP-01
- Isotype
- IgG1
- Specificity
- C-Peptide
Mouse anti C-peptide antibody, clone C-PEP-01 recognizes human C-peptide (also known as connecting peptide) a peptide released when proinsulin is cleaved to produce insulin. It can also be used to detect proinsulin. |
- Target Species
- Human
- Product Form
- Purified IgG - liquid
- Preparation
- Purified IgG prepared by sequential precipitation with caprylic acid and ammonium sulphate from ascites
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- <0.1% Sodium Azide (NaN3)
- Immunogen
- Human C-peptide conjugated to BSA.
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
Application Name | Verified | Min Dilution | Max Dilution |
---|---|---|---|
Immunohistology - Frozen |
References for C-Peptide antibody
-
Hilgert, I. et al. (1991) A monoclonal antibody applicable for determination of C-peptide of human proinsulin by RIA.
Hybridoma. 10: 379-86. -
Afrikanova, I. et al. (2011) Inhibitors of Src and focal adhesion kinase promote endocrine specification: impact on the derivation of β-cells from human pluripotent stem cells.
J Biol Chem. 286 (41): 36042-52.
Further Reading
-
Vasic, D. & Walcher, D. (2012) C-peptide: a new mediator of atherosclerosis in diabetes.
Mediators Inflamm. 2012: 858692.
- RRID
- AB_617247
- UniProt
- P01308
- Entrez Gene
- INS
- GO Terms
- GO:0000165 MAPKKK cascade
- GO:0002674 negative regulation of acute inflammatory response
- GO:0006953 acute-phase response
- GO:0005158 insulin receptor binding
- GO:0005159 insulin-like growth factor receptor binding
- GO:0005179 hormone activity
- GO:0005615 extracellular space
- GO:0005788 endoplasmic reticulum lumen
- GO:0006006 glucose metabolic process
- View More GO Terms
- GO:0006112 energy reserve metabolic process
- GO:0006521 regulation of cellular amino acid metabolic process
- GO:0007186 G-protein coupled receptor protein signaling pathway
- GO:0007267 cell-cell signaling
- GO:0050796 regulation of insulin secretion
- GO:0008284 positive regulation of cell proliferation
- GO:0008286 insulin receptor signaling pathway
- GO:0008543 fibroblast growth factor receptor signaling pathway
- GO:0045909 positive regulation of vasodilation
- GO:0014068 positive regulation of phosphatidylinositol 3-kinase cascade
- GO:0015758 glucose transport
- GO:0046326 positive regulation of glucose import
- GO:0046889 positive regulation of lipid biosynthetic process
- GO:0022898 regulation of transmembrane transporter activity
- GO:0030307 positive regulation of cell growth
- GO:0030335 positive regulation of cell migration
- GO:0031018 endocrine pancreas development
- GO:0031904 endosome lumen
- GO:0031954 positive regulation of protein autophosphorylation
- GO:0032148 activation of protein kinase B activity
- GO:0032583 regulation of gene-specific transcription
- GO:0033861 negative regulation of NAD(P)H oxidase activity
- GO:0042060 wound healing
- GO:0042177 negative regulation of protein catabolic process
- GO:0042593 glucose homeostasis
- GO:0043066 negative regulation of apoptosis
- GO:0043410 positive regulation of MAPKKK cascade
- GO:0045429 positive regulation of nitric oxide biosynthetic process
- GO:0045597 positive regulation of cell differentiation
- GO:0045721 negative regulation of gluconeogenesis
- GO:0045725 positive regulation of glycogen biosynthetic process
- GO:0045740 positive regulation of DNA replication
- GO:0045818 negative regulation of glycogen catabolic process
- GO:0045821 positive regulation of glycolysis
- GO:0045840 positive regulation of mitosis
- GO:0045861 negative regulation of proteolysis
- GO:0045908 negative regulation of vasodilation
- GO:0045922 negative regulation of fatty acid metabolic process
- GO:0046628 positive regulation of insulin receptor signaling pathway
- GO:0046631 alpha-beta T cell activation
- GO:0050709 negative regulation of protein secretion
- GO:0050715 positive regulation of cytokine secretion
- GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation
- GO:0050995 negative regulation of lipid catabolic process
- GO:0051000 positive regulation of nitric-oxide synthase activity
- GO:0051092 positive regulation of NF-kappaB transcription factor activity
- GO:0051897 positive regulation of protein kinase B signaling cascade
- GO:0055089 fatty acid homeostasis
- GO:0060266 negative regulation of respiratory burst involved in inflammatory response
- GO:0060267 positive regulation of respiratory burst
1700-0204
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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