Beta Amyloid antibody | DE2B4
In immunohistology the antibody detects extracellular amyloid beta with senile plaques and vessel amyloid in Alzheimer's disease brain.
- Target Species
- Product Form
- Purified IgG - liquid
- Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
0.09% Sodium Azide
- Carrier Free
- Synthetic peptide consisting of residues 1 - 17 of the amyloid beta protein.
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
- Store at +4oC or at -20oC if preferred.
This product should be stored undiluted.
Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
- 18 months from date of despatch.
- P05067 Related reagents
- Entrez Gene
- APP Related reagents
- For research purposes only
Applications of Beta Amyloid antibody
|Application Name||Verified||Min Dilution||Max Dilution|
|Immunohistology - Paraffin 1|
- 1This product requires protein digestion pre-treatment of paraffin sections using formic acid for 2-3 minutes.
- Histology Positive Control Tissue
- Alzheimer's disease brain
Secondary Antibodies Available
Application Based External Images
Immunohistology - Paraffin
Product Specific References
References for Beta Amyloid antibody
Kitamoto, T. et al. (1987) Formic acid pretreatment enhances immunostaining of cerebral and systemic amyloids.
Lab Invest. 57 (2): 230-6.
Lee, M.H. et al. (2010) TGF-β induces TIAF1 self-aggregation via type II receptor-independent signaling that leads to generation of amyloid β plaques in Alzheimer's disease.
Cell Death Dis. 1: e110.
Chang, J.Y. et al. (2012) TIAF1 self-aggregation in peritumor capsule formation, spontaneous activation of SMAD-responsive promoter in p53-deficient environment, and cell death.
Cell Death Dis. 3: e302.
Koronyo-Hamaoui, M. et al. (2011) Identification of amyloid plaques in retinas from Alzheimer's patients and noninvasive in vivo optical imaging of retinal plaques in a mouse model.
Neuroimage. 54 Suppl 1: S204-17.
Chang, J.Y. et al. (2015) Trafficking protein particle complex 6A delta (TRAPPC6AΔ) is an extracellular plaque-forming protein in the brain.
Oncotarget. 6 (6): 3578-89.