Atrial Natriuretic Peptide antibody | 23/1

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Mouse anti Human Atrial Natriuretic Peptide

Product Type
Monoclonal Antibody
Clone
23/1
Isotype
IgG1
Product CodeApplicationsDatasheetMSDSPack SizeList PriceQuantity
0200-0648 P R 1 mg
Mouse anti Human Atrial Natriuretic Peptide antibody, clone 23/1 Recognizes noth the whole human atrial natriuretic peptide and the c terminal fragment (amino acids 4-28). ANP is formed by the cleavage of the holo Natriuretic peptides A by CORIN to release functionally active ANP.

Product Details

Target Species
Human
Product Form
Purified IgG - liquid
Preparation
Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.1% Sodium Azide (NaN3)
Immunogen
Synthetic peptide corresponding to part of the native molecule conjugated to bovine serum albumin.
Approx. Protein Concentrations
IgG concentration 1.0 mg/ml

Storage Information

Storage
Store at +4oC or at -20oC if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted.
Avoid repeated freezing and thawing as this may denature the antibody.
Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life
18 months from date of despatch.

More Information

UniProt
P01160 Related reagents
Entrez Gene
NPPA Related reagents
GO Terms
GO:0005576 extracellular region
GO:0005179 hormone activity
GO:0006182 cGMP biosynthetic process
GO:0007168 receptor guanylyl cyclase signaling pathway
GO:0008217 regulation of blood pressure
GO:0050880 regulation of blood vessel size
Regulatory
For research purposes only

Applications of Atrial Natriuretic Peptide antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Immunohistology - Paraffin
Radioimmunoassays
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using the appropriate negative/positive controls.
Competitive radioimmunoassay (clinical measurement of circulating ANP levels, possibly in conjunction with cyclic GMP). Liquid phase assay without plasma extraction.

Product Specific References

References for Atrial Natriuretic Peptide antibody

  1. Shan, X. et al. (2008) Apoptosis signal-regulating kinase 1 attenuates atrial natriuretic peptide secretion.
    Biochemistry. 47: 10041-8.
  2. Chen, J.H. et al. (2012) Pathophysiology of sudden cardiac death as demonstrated by molecular pathology of natriuretic peptides in the myocardium.
    Forensic Sci Int. 223 (1-3): 342-8.