Angiotensin I/II/III antibody | 08/56a/A2.21 (BGN/0856/21)
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Mousae anti Human Angiotensin antibody, clone 08/56a/A2.21 recognizes Angiotensin I, Angiotensin II and Angiotensin III in ELISA.
Incomplete mapping indicates that the epitope is VYIHP (corresponding to amino acids 3-8 of Angiotensin I & II), a conserved region found in all Angiotensin molecules.
Incomplete mapping indicates that the epitope is VYIHP (corresponding to amino acids 3-8 of Angiotensin I & II), a conserved region found in all Angiotensin molecules.
Product Details
- Target Species
- Human
- Product Form
- Purified IgG - liquid
- Preparation
- Purified IgG prepared by affinity chromatography on Protein G from ascites.
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3)
- Immunogen
- Synthetic peptide representing Angiotensin II, conjugated to rabbit albumin.
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
Storage Information
- Storage
- This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended. - Guarantee
- 12 months from date of despatch
More Information
- UniProt
- P01019
- Entrez Gene
- AGT
- GO Terms
- GO:0001819 positive regulation of cytokine production
- GO:0001822 kidney development
- GO:0001974 blood vessel remodeling
- GO:0002018 renin-angiotensin regulation of aldosterone production
- GO:0002019 regulation of renal output by angiotensin
- GO:0003078 regulation of natriuresis
- GO:0004867 serine-type endopeptidase inhibitor activity
- GO:0005179 hormone activity
- GO:0005615 extracellular space
- GO:0005625 soluble fraction
- GO:0006800 oxygen and reactive oxygen species metabolic process
- GO:0007199 G-protein signaling, coupled to cGMP nucleotide second messenger
- GO:0007200 activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger
- GO:0007263 nitric oxide mediated signal transduction
- GO:0007267 cell-cell signaling
- GO:0008083 growth factor activity
- GO:0010595 positive regulation of endothelial cell migration
- GO:0010613 positive regulation of cardiac muscle hypertrophy
- GO:0010698 acetyltransferase activator activity
- GO:0010744 positive regulation of macrophage derived foam cell differentiation
- GO:0010873 positive regulation of cholesterol esterification
- GO:0014068 positive regulation of phosphatidylinositol 3-kinase cascade
- GO:0014873 response to muscle activity involved in regulation of muscle adaptation
- GO:0019229 regulation of vasoconstriction
- GO:0031702 type 1 angiotensin receptor binding
- GO:0031703 type 2 angiotensin receptor binding
- GO:0033864 positive regulation of NAD(P)H oxidase activity
- GO:0034374 low-density lipoprotein particle remodeling
- GO:0043065 positive regulation of apoptosis
- GO:0044255 cellular lipid metabolic process
- GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway
- GO:0048146 positive regulation of fibroblast proliferation
- GO:0050729 positive regulation of inflammatory response
- GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation
- GO:0051092 positive regulation of NF-kappaB transcription factor activity
- GO:0051387 negative regulation of nerve growth factor receptor signaling pathway
- Regulatory
- For research purposes only
Applications of Angiotensin I/II/III antibody
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| ELISA | 1/10 | 1/100 |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using the appropriate negative/positive controls.
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