Angiotensin I/II/III antibody | 08/56a/A2.21 (BGN/0856/21)

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Mouse anti Human Angiotensin I/II/III

Product Type: Monoclonal Antibody
Clone: 08/56a/A2.21 (BGN/0856/21)
Isotype: IgG1

Product Code	Applications	Datasheet	MSDS	Pack Size	List Price	Quantity
0100-0556	E			0.2 mg

Summary
Secondary Antibodies

Mousae anti Human Angiotensin antibody, clone 08/56a/A2.21 recognizes Angiotensin I, Angiotensin II and Angiotensin III in ELISA.

Incomplete mapping indicates that the epitope is VYIHP (corresponding to amino acids 3-8 of Angiotensin I & II), a conserved region found in all Angiotensin molecules.

Product Details

Target Species: Human
Product Form: Purified IgG - liquid
Preparation: Purified IgG prepared by affinity chromatography on Protein A.
Buffer Solution: Phosphate buffered saline
Preservative Stabilisers: 0.09% Sodium Azide (NaN₃)
Immunogen: Synthetic peptide representing Angiotensin II, conjugated to rabbit albumin.
Approx. Protein Concentrations: IgG concentration 1.0 mg/ml

Storage Information

Storage: Store at +4^oC or at -20^oC if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.

More Information

UniProt: P01019 Related reagents
Entrez Gene: AGT Related reagents
GO Terms: GO:0001819 positive regulation of cytokine production; GO:0001822 kidney development; GO:0001974 blood vessel remodeling; GO:0002018 renin-angiotensin regulation of aldosterone production; GO:0002019 regulation of renal output by angiotensin; GO:0003078 regulation of natriuresis; GO:0004867 serine-type endopeptidase inhibitor activity; GO:0005179 hormone activity; GO:0005615 extracellular space; GO:0005625 soluble fraction; GO:0006800 oxygen and reactive oxygen species metabolic process; GO:0007199 G-protein signaling, coupled to cGMP nucleotide second messenger; GO:0007200 activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger; GO:0007263 nitric oxide mediated signal transduction; GO:0007267 cell-cell signaling; GO:0008083 growth factor activity; GO:0010595 positive regulation of endothelial cell migration; GO:0010613 positive regulation of cardiac muscle hypertrophy; GO:0010698 acetyltransferase activator activity; GO:0010744 positive regulation of macrophage derived foam cell differentiation; GO:0010873 positive regulation of cholesterol esterification; GO:0014068 positive regulation of phosphatidylinositol 3-kinase cascade; GO:0014873 response to muscle activity involved in regulation of muscle adaptation; GO:0019229 regulation of vasoconstriction; GO:0031702 type 1 angiotensin receptor binding; GO:0031703 type 2 angiotensin receptor binding; GO:0033864 positive regulation of NAD(P)H oxidase activity; GO:0034374 low-density lipoprotein particle remodeling; GO:0043065 positive regulation of apoptosis; GO:0044255 cellular lipid metabolic process; GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway; GO:0048146 positive regulation of fibroblast proliferation; GO:0050729 positive regulation of inflammatory response; GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation; GO:0051092 positive regulation of NF-kappaB transcription factor activity; GO:0051387 negative regulation of nerve growth factor receptor signaling pathway
Regulatory: For research purposes only

Applications of Angiotensin I/II/III antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.

Application Name	Verified	Min Dilution	Max Dilution
ELISA		1/10	1/100

Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using the appropriate negative/positive controls.

Secondary Antibodies Available

Description	Product Code	Pack Size	Applications
Goat anti Mouse IgG (H/L):Alk. Phos. (Multi Species Adsorbed)	STAR117A	0.5 mg	E WB
Goat anti Mouse IgG (H/L):DyLight®488 (Multi Species Adsorbed)	STAR117D488GA	0.1 mg	F IF
Goat anti Mouse IgG (H/L):DyLight®549 (Multi Species Adsorbed)	STAR117D549GA	0.1 mg	F IF WB
Goat anti Mouse IgG (H/L):DyLight®649 (Multi Species Adsorbed)	STAR117D649GA	0.1 mg	F IF
Goat anti Mouse IgG (H/L):DyLight®680 (Multi Species Adsorbed)	STAR117D680GA	0.1 mg	F WB
Goat anti Mouse IgG (H/L):DyLight®800 (Multi Species Adsorbed)	STAR117D800GA	0.1 mg	F IF WB
Goat anti Mouse IgG (H/L):FITC (Multi Species Adsorbed)	STAR117F	0.5 mg	F
Goat anti Mouse IgG (H/L):HRP (Multi Species Adsorbed)	STAR117P	0.5 mg	E WB
Goat anti Mouse IgG (Fc):FITC	STAR120F	1 mg	C F
Goat anti Mouse IgG (Fc):HRP	STAR120P	1 mg	E WB
Rabbit F(ab')2 anti Mouse IgG:RPE	STAR12A	1 ml	F
Rabbit F(ab')2 anti Mouse IgG:HRP (Human Adsorbed)	STAR13B	1 mg	C E P RE WB
Goat anti Mouse IgG:FITC (Rat Adsorbed)	STAR70	0.5 mg	F
Goat anti Mouse IgG:RPE (Rat Adsorbed)	STAR76	1 ml	F
Goat anti Mouse IgG:HRP (Rat Adsorbed)	STAR77	0.5 mg	C E P
Goat anti Mouse IgG/A/M:Alk. Phos.	STAR87A	1 mg	C E WB
Goat anti Mouse IgG/A/M:HRP (Human Adsorbed)	STAR87P	1 mg	E
Rabbit F(ab')2 anti Mouse IgG:Dylight®800	STAR8D800GA	0.1 mg	F IF WB
Rabbit F(ab')2 anti Mouse IgG:FITC	STAR9B	1 mg	F

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