AMPK Beta 2 antibody | AB03/2F11
Mouse anti Human AMPK Beta 2
- Product Type
- Monoclonal Antibody
- Clone
- AB03/2F11
- Isotype
- IgG1
- Specificity
- AMPK Beta 2
Antibody Quality and Performance Guarantee
| Mouse anti human AMPK BETA 2 antibody, clone AB03/2F11 recognizes 5'-AMP-activated protein kinase subunit beta-2, also known as PRKAB2. AMPK BETA 2 is part of the serine/threonine kinase family and is expressed in the liver and skeletal muscle. AMPK has been seen to inhibit cellular proliferation and in turn act as a tumor suppressor. This has particularly been seen in liver, lung and colorectal cancer (Li et al. 2015). |
- Target Species
- Human
- Product Form
- Purified IgG - liquid
- Preparation
- Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3)
- Immunogen
- E. coli-derived recombinant protein, aa 1-272 of human AMPK Beta 2.
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Western Blotting |  |
1/1,000 | 1/2,000 |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
- Western Blotting
- Mouse anti human AMPK Beta 2 detects a band of approximately 32 kDa in HepG2 cell lysates.
- UniProt
- O43741
- Entrez Gene
- PRKAB2
- GO Terms
- GO:0005829 cytosol
- GO:0005654 nucleoplasm
- GO:0006112 energy reserve metabolic process
- GO:0006633 fatty acid biosynthetic process
- GO:0006853 carnitine shuttle
- GO:0007050 cell cycle arrest
- GO:0008286 insulin receptor signaling pathway
- GO:0042304 regulation of fatty acid biosynthetic process
- GO:0046320 regulation of fatty acid oxidation
- View More GO Terms
MCA6428GA
100007868
If you cannot find the batch/lot you are looking for please contact our technical support team for assistance.
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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