Mouse anti Human adiponectin antibody, clone D05-9C7,
recognizes adiponectin, also known as ACRP30, apM-1, ADIPOQ. Adiponectin is a fat-derived hormone which suppresses glucose production in the liver and enhances fatty acid oxidation in skeletal muscle, and acts as a messenger to allow communication between adipose tissue and other organs (Wang and Scherer, 2016
). Adiponectin can elicit several downstream signaling events, including the insulin signaling pathway. Anti-diabetic, anti-inflammatory, and anti-atherogenic effects of adiponectin have been identified, and the protein sensitizes cells to insulin. Decreased adiponecin levels may play a role in development of type 2 diabetes, and therefore, adiponectin has been suggested as a potential therapeutic target for diabetes (Achari and Jain 2017
The purified Mouse anti Human adiponectin antibody, clone D05-9C7 can be used as a capture antibody in a sandwich ELISA with the biotinylated Mouse anti Human adiponectin antibody, clone D02-7B10 (MCA6175B
) as the detection antibody.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Applications of Adiponectin antibody
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.