CD8 Beta antibody | CA15.4G2
Mouse anti Dog CD8 Beta
- Product Type
- Monoclonal Antibody
- Clone
- CA15.4G2
- Isotype
- IgG1
- Specificity
- CD8 Beta
Antibody Quality and Performance Guarantee
| Mouse anti Dog CD8 beta antibody, clone CA15.4G2 recognises the canine CD8β cell surface antigen, expressed by cytotoxic\suppressor T lymphocytes that interact with MHC Class I expressing targets. |
- Target Species
- Dog
- Product Form
- Tissue culture supernatant - liquid
- Preservative Stabilisers
- <0.1% sodium azide (NaN3)
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Flow Cytometry |  |
Neat | |
| Immunohistology - Frozen 1 | |
1/10 | |
| Immunohistology - Paraffin | |||
| Immunoprecipitation | |
- 1The epitope recognised by this antibody is reported to be sensitive to formaldehyde fixation and tissue processing. Bio-Rad recommends the use of acetone fixation for frozen sections.
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
- Flow Cytometry
- Use 20μl of the suggested working dilution to label 106 cells or 100μl whole blood
| Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
|---|---|---|---|---|---|---|---|
| Mouse IgG1 Negative Control | MCA928 | F | 100 Tests |
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| List Price | Your Price | ||||||
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| Description | Mouse IgG1 Negative Control | ||||||
References for CD8 Beta antibody
-
Moreno, J. et al. (1999) The immune response and PBMC subsets in canine visceral leishmaniasis before, and after, chemotherapy.
Vet Immunol Immunopathol. 71: 181-95. -
Vernau, W. and Moore, P.F. (1999) An immunophenotypic study of canine leukemias and preliminary assessment of clonality by polymerase chain reaction.
Vet Immunol Immunopathol. 69: 145-64. -
Sonea, I.M. et al. (2000) Flow cytometric analysis of colonic and small intestinal mucosal lymphocytes obtained by endoscopic biopsy in the healthy dog.
Vet Immunol Immunopathol. 77: 103-19. -
Pumarola, M. et al. (2004) Canine inflammatory myopathy: analysis of cellular infiltrates.
Muscle Nerve. 29: 782-9. -
Wilkerson, M.J. et al. (2005) Lineage differentiation of canine lymphoma/leukemias and aberrant expression of CD molecules.
Vet Immunol Immunopathol. 106: 179-96. -
Gauthier, M.J. et al. (2005) The immunophenotype of peripheral blood lymphocytes in clinically healthy dogs and dogs with lymphoma in remission.
J Vet Intern Med. 19: 193-9. -
Kisseberth, W.C. et al. (2007) A novel canine lymphoma cell line: a translational and comparative model for lymphoma research.
Leuk Res. 31: 1709-20. -
Luckschander, N. et al. (2009) Phenotyping, functional characterization, and developmental changes in canine intestinal intraepithelial lymphocytes.
Vet Res. 40: 58.
View The Latest Product References
-
Izci C et al. (2015) Clinical and light microscopic studies of the conjunctival tissues of dogs with bilateral keratoconjunctivitis sicca before and after treatment with topical 2% cyclosporine.
Biotech Histochem. 90 (3): 223-30.
Further Reading
-
Moore, P.F. et al. (1992) Monoclonal antibodies specific for canine CD4 and CD8 define functional T lymphocyte subsets and high density expression of CD4 by canine neutrophils.
Tissue Antigens 40: 75-85.
- RRID
- AB_1220541
MCA1775S
150185
168664
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