CD11c antibody | CA11.6A1


Mouse anti Dog CD11c, clone CA11.6A1 immunoprecipitates proteins of approximately 95 kDa, corresponding to the common β chain of the CD11/CD18 heterodimer and ~150 kDa, the CD11c; chain from canine leukocyte preparations (Danilenko et al. 1992)
Product Details
- Target Species
- Dog
- Species Cross-Reactivity
-
Target Species Cross Reactivity Hooded Seal Raccoon - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Tissue Culture Supernatant - liquid
- Preservative Stabilisers
0.1% Sodium Azide
Storage Information
- Storage
- Store at +4oC or at -20oC if preferred.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. - Guarantee
- 12 months from date of despatch
More Information
- Regulatory
- For research purposes only
Applications of CD11c antibody
Application Name | Verified | Min Dilution | Max Dilution |
---|---|---|---|
Flow Cytometry | |||
Immunohistology - Frozen 1 | |||
Immunohistology - Paraffin | |||
Immunoprecipitation |
- 1The epitope recognised by this antibody is reported to be sensitive to formaldehyde fixation and tissue processing. Bio-Rad recommends the use of acetone fixation for frozen sections.
- Flow Cytometry
- Use 10ul of the suggested working dilution to label 106 cells or 100ul whole blood
Secondary Antibodies Available
Negative Isotype Controls Available
Description | Product Code | Applications | Pack Size | List Price | Quantity |
---|---|---|---|---|---|
Mouse IgG1 Negative Control | MCA928 | F | 100 Tests |
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Product Specific References
References for CD11c antibody
-
Danilenko, D.M. et al. (1992) Canine leukocyte cell adhesion molecules (LeuCAMS): characterization of the CD11/CD18 family.
Tissue Antigens 40: 13-21. -
Kang, J.W. et al. (2008) Soluble factors-mediated immunomodulatory effects of canine adipose tissue-derived mesenchymal stem cells.
Stem Cells Dev. 17: 681-93. -
Affolter, V.K. and Moore, P.F. (2002) Localized and disseminated histiocytic sarcoma of dendritic cell origin in dogs.
Vet Pathol. 39: 74-83. -
Bird, R.C. et al. (2008) An allogeneic hybrid-cell fusion vaccine against canine mammary cancer.
Vet Immunol Immunopathol. 123: 289-304. -
Catchpole, B. et al. (2002) Generation of blood-derived dendritic cells in dogs with oral malignant melanoma.
J Comp Pathol. 126: 238-41. -
Isotani, M. et al. (2006) Efficient generation of canine bone marrow-derived dendritic cells.
J Vet Med Sci. 68: 809-14. -
Liu, C.C. et al. (2008) Transient downregulation of monocyte-derived dendritic-cell differentiation, function, and survival during tumoral progression and regression in an in vivo canine model of transmissible venereal tumor.
Cancer Immunol Immunother. 57: 479-91. -
McDonough, S.P. and Moore, P.F. (2000) Clinical, hematologic, and immunophenotypic characterization of canine large granular lymphocytosis.
Vet Pathol. 37: 637-46. -
Wang, Y.S. et al. (2007) Characterization of canine monocyte-derived dendritic cells with phenotypic and functional differentiation.
Can J Vet Res. 71: 165-74. -
Mathes, M. et al. (2006) Evaluation of liposomal clodronate in experimental spontaneous autoimmune hemolytic anemia in dogs.
Exp Hematol. 34: 1393-402. -
Sanchez, M.A. et al. (2004) Organ-specific immunity in canine visceral leishmaniasis: analysis of symptomatic and asymptomatic dogs naturally infected with Leishmania chagasi.
Am J Trop Med Hyg. 70: 618-24. -
Ricklin Gutzwiller, M.E. et al. (2010) Comparative analysis of canine monocyte- and bone-marrow-derived dendritic cells.
Vet Res. 41: 40. -
Ibisch, C. et al. (2005) Functional canine dendritic cells can be generated in vitro from peripheral blood mononuclear cells and contain a cytoplasmic ultrastructural marker.
J Immunol Methods. 298: 175-82. -
Wang, Y.S. et al. (2008) Cytokine profiles of canine monocyte-derived dendritic cells as a function of lipopolysaccharide- or tumor necrosis factor-alpha-induced maturation.
Vet Immunol Immunopathol. 118: 186-98. -
Schwartz, M. et al. (2008) Selective CD11a upregulation on neutrophils in the acute phase of steroid-responsive meningitis-arteritis in dogs.
Vet Immunol Immunopathol. 126: 248-55. -
Pai, C.C. et al. (2011) Immunopathogenic behaviors of canine transmissible venereal tumor in dogs following an immunotherapy using dendritic/tumor cell hybrid.
Vet Immunol Immunopathol. 139 (2-4): 187-99. -
Figueiredo, M.M. et al. (2013) Expression of Toll-like Receptors 2 and 9 in cells of dog jejunum and colon naturally infected with Leishmania infantum.
BMC Immunol. 14: 22. -
Larsen, A.K. et al. (2013) Entry and elimination of marine mammal Brucella spp. by hooded seal (Cystophora cristata) alveolar macrophages in vitro.
PLoS One. 8: e70186. -
Heinrich, F. et al. (2015) Immunophenotyping of immune cell populations in the raccoon (Procyon lotor).
Vet Immunol Immunopathol. 168 (3-4): 140-6. -
Paoloni, M. et al. (2015) Defining the Pharmacodynamic Profile and Therapeutic Index of NHS-IL12 Immunocytokine in Dogs with Malignant Melanoma.
PLoS One. 10 (6): e0129954. -
Bonnefont-Rebeix, C. et al. (2016) Characterization of a novel canine T-cell line established from a spontaneously occurring aggressive T-cell lymphoma with large granular cell morphology.
Immunobiology. 221 (1): 12-22. -
Constantinoiu, C.C. et al. (2015) Mucosal tolerance of the hookworm Ancylostoma caninum in the gut of naturally infected wild dogs.
Parasite Immunol. Jul 27 [Epub ahead of print]. -
Stokol, T. et al. (2015) Alkaline phosphatase is a useful cytochemical marker for the diagnosis of acute myelomonocytic and monocytic leukemia in the dog.
Vet Clin Pathol. 44 (1): 79-93. -
Heinrich, F. et al. (2015) Passage-dependent morphological and phenotypical changes of a canine histiocytic sarcoma cell line (DH82 cells).
Vet Immunol Immunopathol. 163 (1-2): 86-92. -
Qeska, V. et al. (2014) Canine distemper virus infection leads to an inhibitory phenotype of monocyte-derived dendritic cells in vitro with reduced expression of co-stimulatory molecules and increased interleukin-10 transcription.
PLoS One. 9 (4): e96121. -
Bird, R.C. et al. (2019) Autologous hybrid cell fusion vaccine in a spontaneous intermediate model of breast carcinoma.
J Vet Sci. 20 (5): e48.
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