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Apolipoprotein H Antibody | ID2
Staining of an 8.6 week placenta stained with Mouse anti Human Apolipoprotein H (MCA2114)
Enlarge- Mouse anti Human Apolipoprotein H
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Product TypeMonoclonal Antibody
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CloneID2
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IsotypeIgG1
1 Formats Available
| Product Code | Applications | Datasheet | MSDS | Pack Size | List Price | Quantity |
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Summary
Secondary Antibodies
Negative Isotype Controls
Useful Reagents
Positive Controls
Histology Controls
More Images
References
Reviews
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- Mouse anti Human apolipoprotein H antibody, clone 1D2 recognises the human Apolipoprotein H molecule, also known as beta 2 glycoprotein 1, APC inhibitor, activated protein C-binding protein or anticardiolipin cofactor. Apolipoprotein H is expressed by placental trophoblast cells at high levels. Although the normal physiological role is not known, the protein appears to act as a co-factor for the binding of autoantibodies to phospholipids to trophoblasts, a process involved in the pathogenesis of recurrent miscarriage and thrombotic tendencies due to antiphospholipid syndrome.
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Intended Use
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Target SpeciesHuman
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Product FormTissue Culture Supernatant - liquid
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Reconstitution
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Preparation
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Preservative Stabilisers
0.09% Sodium Azide -
Purity
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Approx. Protein Concentrations
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Reagents In The Kit
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Preparing The Antibody
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Test Principle
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Buffer Solution
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StorageStore at +4oC or at -20oC if preferred.
This product should be stored undiluted.
Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. -
Shelf Life18 months from date of despatch.
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GO Termsnegative regulation of fibrinolysisplasminogen activationlipoprotein lipase activator activitynegative regulation of angiogenesisnegative regulation of endothelial cell migrationphospholipid bindingtriglyceride metabolic processchylomicronglycoprotein bindingeukaryotic cell surface bindingnegative regulation of smooth muscle cell apoptosispositive regulation of lipoprotein lipase activityhigh-density lipoprotein particletriglyceride transportnegative regulation of blood coagulationcell surfacenegative regulation of endothelial cell proliferationvery-low-density lipoprotein particleheparin bindingnegative regulation of myeloid cell apoptosisblood coagulation, intrinsic pathway
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UniProt
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Entrez Gene
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Acknowledgements
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RegulatoryFor research purposes only
- This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Yes No Min Dilution Max Dilution Immunohistology - Frozen Western Blotting - Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive control.
- Technical Advice
- Recommended Protocol
- ELISA
- Immunohistology
- Histology Positive Control TissuePlacenta
- Immunofluorescence
- Western Blotting
- Instructions For Use
Additional Apolipoprotein H Antibody Formats
| Formats | Clone | Applications | Sizes available |
|---|---|---|---|
| Apolipoprotein H Antibody : S/N | ID2 | C, WB | 2 ml |
- Copyright © 2018 Bio-Rad Antibodies (formerly AbD Serotec)
Recommended Secondary Antibody
Recommended Negative Isotype Control
Useful Reagents
Recommended Positive Controls
Histology Controls
Placenta
References
1. Mak, I.Y. et al. (2002) Regulated expression of signal transducer and activator of transcription, Stat5, and its enhancement of PRL expression in human endometrial stromal cells in vitro.J Clin Endocrinol Metab. 87 (6): 2581-8.
2. Vlachoyiannopoulos, P.G. et al. (2004) Anti-CD40 antibodies in antiphospholipid syndrome and systemic lupus erythematosus.Thromb Haemost. 92: 1303-11.
3. Lopez, D. et al. (2004) Oxidized low-density lipoprotein/beta2-glycoprotein I complexes and autoantibodies to oxLig-1/beta2-glycoprotein I in patients with systemic lupus erythematosus and antiphospholipid syndrome.Am J Clin Pathol. 121 (3): 426-36.
Further Reading
1. Chamley, L.W. et al. (2001) Is interleukin-3 important in antiphospholipid antibody-mediated pregnancy failure?Fertil Steril. 76 (4): 700-6.
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Copyright © 2018 Bio-Rad Laboratories, Inc. All rights reserved
Copyright © 2018 Bio-Rad Laboratories, Inc. All rights reserved
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