IgG3 antibody | LO-MG3-13
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Rat anti Mouse IgG3
- Product Type
- Monoclonal Antibody
- Clone
- LO-MG3-13
- Isotype
- IgG1
- Specificity
- IgG3
- Region
- HEAVY CHAIN
Antibody Quality and 
Unrivaled 
| Rat anti Mouse IgG3 antibody, clone LO-MG3-13 recognizes murine IgG3 (gamma heavy chain) and does not cross react with other murine immunoglobulin classes or subclasses. |
- Target Species
- Mouse
- Product Form
- Purified IgG - liquid
- Preparation
- Purified IgG prepared by affinity chromatography on mouse IgG3/Sepharose 4B from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.1% Sodium Azide (NaN3)
- Immunogen
- Polyclonal mouse IgG
- Approx. Protein Concentrations
- IgG concentration 1 mg/ml
- Fusion Partners
- Spleen cells from immunized Lou/c rats were fused with cells of the rat IR983F myeloma cell line.
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| ELISA |  |
5ug/ml (coating) |
Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
References for IgG3 antibody
-
Denis, O. et al. (1993) Resting B cells can act as antigen presenting cells in vivo and induce antibody responses.
Int Immunol. 5 (1): 71-8. -
Savignac, M. et al. (2010) Increased B cell proliferation and reduced Ig production in DREAM transgenic mice.
J Immunol. 185 (12): 7527-36. -
Banerjee, K. et al. (2009) Enzymatic removal of mannose moieties can increase the immune response to HIV-1 gp120 in vivo.
Virology. 389 (1-2): 108-21. -
Banerjee, K. et al. (2012) Occluding the mannose moieties on human immunodeficiency virus type 1 gp120 with griffithsin improves the antibody responses to both proteins in mice.
AIDS Res Hum Retroviruses. 28 (2): 206-14.
- RRID
- AB_321848
- UniProt
- P03987
- Entrez Gene
- AI324046
- GO Terms
- GO:0005886 plasma membrane
- GO:0003823 antigen binding
- GO:0016021 integral to membrane
- GO:0005576 extracellular region
View more products with IGG specificity
Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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