IgG2a antibody | LO-MG2a-9
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|Rat anti Mouse IgG2a Heavy Chain antibody, clone LO-MG2a-9 recognizes the mouse gamma 2a heavy chain, binding to all allotypes and does not cross-react with other murine immunoglobulin classes or subclasses.
The avidity of Rat anti Mouse IgG2a Heavy Chain antibody, clone LO-MG2a-9 for murine IgG2a = 2.5 x 109M-1.
- Target Species
- Product Form
- Purified IgG - liquid
- Purified IgG prepared by affinity chromatography from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.1% sodium azide (NaN3)
- Purified IgG2a from Balb/c mice. PTR
- Approx. Protein Concentrations
- IgG concentration 1 mg/ml
- Fusion Partners
- Spleen cells from an immunized LOU/c rat were fused with cells of the IR983F rat myeloma cell line.
- For research purposes only
- 12 months from date of despatch
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
|Application Name||Verified||Min Dilution||Max Dilution|
|ELISA||5ug/ml as coating antibody|
- This antibody may be used as a coating antibody in sandwich ELISA in combination with LO-MG2a-7 (MCA421P) as the detection reagent.
References for IgG2a antibody
Lahat, G. et al. (2010) Vimentin is a novel anti-cancer therapeutic target; insights from in vitro and in vivo mice xenograft studies.
PLoS One. 5(4):e10105.
Savignac. M. et al. (2010) Increased B cell proliferation and reduced Ig production in DREAM transgenic mice.
J Immunol. 185:7527-36.
Echeverria, P.C. et al. (2006) Potent antigen-specific immunity to Toxoplasma gondii in adjuvant-free vaccination system using Rop2-Leishmania infantum Hsp83 fusion protein.
Vaccine. 24: 4102-10.
Hajek, A.R. et al. (2008) 12/15-Lipoxygenase deficiency protects mice from allergic airways inflammation and increases secretory IgA levels.
J Allergy Clin Immunol. 122: 633-9.e3.
Carew, J.S. et al. (2015) Targeting Survivin Inhibits Renal Cell Carcinoma Progression and Enhances the Activity of Temsirolimus.
Mol Cancer Ther. 14 (6): 1404-13.
Blodörn, K. et al. (2014) Vaccine safety and efficacy evaluation of a recombinant bovine respiratory syncytial virus (BRSV) with deletion of the SH gene and subunit vaccines based on recombinant human RSV proteins: N-nanorings, P and M2-1, in calves with maternal antibodies.
PLoS One. 9 (6): e100392.
Islam, S. et al. (2020) Resistance to histone deacetylase inhibitors confers hypersensitivity to oncolytic reovirus therapy.
Blood Adv. 4 (20): 5297-310.
- Entrez Gene
- GO Terms
- GO:0003823 antigen binding
- GO:0002455 humoral immune response mediated by circulating immunoglobulin
- GO:0019731 antibacterial humoral response
- GO:0042571 immunoglobulin complex, circulating
- GO:0005886 plasma membrane
- GO:0016021 integral to membrane
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