IgG1 antibody | LO-MG1-2
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Rat anti Mouse IgG1 Heavy Chain
- Product Type
- Monoclonal Antibody
- HEAVY CHAIN
|Rat anti Mouse IgG1 Heavy Chain antibody, clone LO-MG1-2 recognizes murine IgG1, and does not bind other mouse immunoglobulin classes or subclasses.|
- Target Species
- Product Form
- Purified IgG - liquid
- Purified IgG prepared by affinity chromatography from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
0.1% Sodium Azide
- Purified mouse IgG1 from BALB/c mice
- Approx. Protein Concentrations
- IgG concentration 1 mg/ml
- Fusion Partners
- Spleen cells from immunised LOU/c rats were fused with cells of the rat IR983F myeloma cell line.
- For research purposes only
- 12 months from date of despatch
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
|Application Name||Verified||Min Dilution||Max Dilution|
|ELISA||5ug/ml as coating antibody|
References for IgG1 antibody
Denis, O. et al. (1993) Resting B cells can act as antigen presenting cells in vivo and induce antibody responses.
Int Immunol. 5 (1): 71-8.
Song, J. et al. (2000) Heterogeneous distribution of isoactins in cultured vascular smooth muscle cells does not reflect segregation of contractile and cytoskeletal domains.
J Histochem Cytochem. 48 (11): 1441-52.
Blackwell, N.M. & Else, K.J. (2002) A comparison of local and peripheral parasite-specific antibody production in different strains of mice infected with Trichuris muris.
Parasite Immunol. 24 (4): 203-11.
Hall, G. et al. (2003) Suppression of allergen reactive Th2 mediated responses and pulmonary eosinophilia by intranasal administration of an immunodominant peptide is linked to IL-10 production.
Vaccine. 21 (5-6): 549-61.
Echeverria, P.C. et al. (2006) Potent antigen-specific immunity to Toxoplasma gondii in adjuvant-free vaccination system using Rop2-Leishmania infantum Hsp83 fusion protein.
Vaccine. 24: 4102-10.
Ramos, J.D.A. et al. (2009) Characterization of Blo t 11 Monoclonal Antibodies with Constant Region Mutations
Phil Sci Lett. 2(1): 38-48
Nakanishi, S. et al. (2010) Sequence analysis of a bacteriocinogenic plasmid of Clostridium butyricum and expression of the bacteriocin gene in Escherichia coli.
Anaerobe. 16: 253-7.
Hjerpe, C. et al. (2010) Dendritic cells pulsed with malondialdehyde modified low density lipoprotein aggravate atherosclerosis in Apoe(-/-) mice.
Atherosclerosis. 209 (2): 436-41.
View The Latest Product References
Huang, C.H. et al. (2011) Airway inflammation and IgE production induced by dust mite allergen-specific memory/effector Th2 cell line can be effectively attenuated by IL-35.
J Immunol. 187: 462-71.
Agallou, M. et al. (2014) Experimental Validation of Multi-Epitope Peptides Including Promising MHC Class I- and II-Restricted Epitopes of Four Known Leishmania infantum Proteins.
Front Immunol. 5: 268.
Kato, G. et al. (2014) β2 adrenergic agonist attenuates house dust mite-induced allergic airway inflammation through dendritic cells.
BMC Immunol. 15: 39.
Doerfler, P.A. et al. (2015) BAFF Blockade Prevents Anti-Drug Antibody Formation in a Mouse Model of Pompe Disease.
Clin Immunol. pii: S1521-6616(15)00125-4.
Kretschmer, B. et al. (2015) Anti-CD83 promotes IgG1 isotype switch in marginal zone B cells in response to TI-2 antigen.
Immunobiology. 220 (8): 964-75.
Doerfler, P.A. et al. (2016) Copackaged AAV9 Vectors Promote Simultaneous Immune Tolerance and Phenotypic Correction of Pompe Disease.
Hum Gene Ther. 27 (1): 43-59.
Margaroni, M. et al. (2017) Vaccination with poly(D,L-lactide-co-glycolide) nanoparticles loaded with soluble Leishmania antigens and modified with a TNFα-mimicking peptide or monophosphoryl lipid A confers protection against experimental visceral leishmaniasis.
Int J Nanomedicine. 12: 6169-84.
Steel, N. et al. (2019) TGFβ-activation by dendritic cells drives Th17 induction and intestinal contractility and augments the expulsion of the parasite Trichinella spiralis. in mice.
PLoS Pathog. 15 (4): e1007657.
DeGiovanni, C. et al. (2019) Cancer Vaccines Co-Targeting HER2/Neu and IGF1R.
Cancers (Basel). 11 (4) Apr 11 [Epub ahead of print].
Scaramozza, A. et al. (2019) Lineage Tracing Reveals a Subset of Reserve Muscle Stem Cells Capable of Clonal Expansion under Stress.
Cell Stem Cell. 24 (6): 944-957.e5.
Salem, E. et al. (2019) Pathogenesis, Host Innate Immune Response, and Aerosol Transmission of Influenza D Virus in Cattle.
Doshi, B.S. et al. (2021) B cell-activating factor modulates the factor VIII immune response in hemophilia A.
J Clin Invest. 131(8):142906.
- Entrez Gene
- GO Terms
- GO:0001788 antibody-dependent cellular cytotoxicity
- GO:0001798 positive regulation of type IIa hypersensitivity
- GO:0001812 positive regulation of type I hypersensitivity
- GO:0003823 antigen binding
- GO:0006910 phagocytosis, recognition
- GO:0006911 phagocytosis, engulfment
- GO:0006958 complement activation, classical pathway
- GO:0019731 antibacterial humoral response
- GO:0042571 immunoglobulin complex, circulating
- View More GO Terms
- GO:0050766 positive regulation of phagocytosis
- GO:0005886 plasma membrane
- GO:0016021 integral to membrane
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