CD38 antibody | 90
Rat anti Mouse CD38
- Product Type
- Monoclonal Antibody
- Clone
- 90
- Isotype
- IgG2a
- Specificity
- CD38
Rat anti Mouse CD38 antibody, clone 90 recognizes the murine CD38 cell surface antigen, a ~42-46kDa glycoprotein expressed by B lymphocytes, a proportion of peripheral T lymphocytes and by peritoneal macrophages. In the mouse CD38 is expressed by follicular B cells, is down regulated on germinal centre B cells, and not expressed by mature plasma cells. This pattern of expression contrasts strikingly with that seen in the human. |
- Target Species
- Mouse
- Product Form
- Purified IgG - liquid
- Preparation
- Purified IgG prepared by affinity chromatography
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- <0.1% sodium azide (NaN3)
- Immunogen
- Mouse pre-B cells derived from IL-7 dependent bone marrow cultures.
- Approx. Protein Concentrations
- IgG concentration 0.5 mg/ml
- Fusion Partners
- Lymph node cells from an immunized rat were fused with cells of the mouse P3X63Ag.8.653 myeloma cell line.
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
Application Name | Verified | Min Dilution | Max Dilution |
---|---|---|---|
Flow Cytometry | 1/2 | 1/20 | |
Immunohistology - Frozen | |||
Immunoprecipitation |
- Flow Cytometry
- Use 10μl of the suggested working dilution to label 106 cells in 100μl
Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
---|---|---|---|---|---|---|---|
Rat IgG2a Negative Control | MCA1212 | E F | 1 ml | Log in | |||
List Price | Your Price | ||||||
Log in | |||||||
Description | Rat IgG2a Negative Control |
References for CD38 antibody
-
Lund, F. et al. (1995) Murine CD38: an immunoregulatory ectoenzyme.
Immunol Today. 16 (10): 469-73. -
Oliver, A.M. et al. (1997) Mouse CD38 is down-regulated on germinal center B cells and mature plasma cells.
J Immunol. 158 (3): 1108-15.
- RRID
- AB_2073336
- UniProt
- P56528
- Entrez Gene
- Cd38
- GO Terms
- GO:0003953 NAD+ nucleosidase activity
- GO:0016021 integral to membrane
- GO:0005488 binding
- GO:0009986 cell surface
- GO:0016849 phosphorus-oxygen lyase activity
- GO:0030890 positive regulation of B cell proliferation
MCA1511R
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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