Macrophages/Monocytes antibody | MOMA-2
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F C P IC IF ResetRat anti Mouse Macrophages/Monocytes
- Product Type
- Monoclonal Antibody
- Clone
- MOMA-2
- Isotype
- IgG2b
- Specificity
- Macrophages/Monocytes
Rat anti Mouse Macrophages/Monocytes antibody, clone MOMA-2 recognizes an intracellular antigen of mouse macrophages and monocytes. It reacts strongly with macrophages in lymphoid organs such as tingible body macrophages and macrophages in T cell dependant areas and is extremely useful in immunohistochemistry. Reacts on all mouse strains tested. |
- Target Species
- Mouse
- Product Form
- MCA519GT: Purified IgG - liquid
- MCA519G: Purified IgG - liquid.
- Preparation
- Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant.
- Buffer Solution
- Phosphate buffered saline.
- Preservative Stabilisers
- <0.1% Sodium Azide (NaN3).
- Immunogen
- Mouse lymph node stroma.
- Approx. Protein Concentrations
- IgG concentration 0.5 mg/ml.
- Fusion Partners
- Spleen cells from immunized Wistar rats were fused with cells of the SP/0 myeloma cell line.
- Regulatory
- For research purposes only.
- Guarantee
- 12 months from date of despatch.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
Application Name | Verified | Min Dilution | Max Dilution |
---|---|---|---|
Flow Cytometry 1 | |||
Immunofluorescence | |||
Immunohistology - Frozen | 1/25 |
- 1 Membrane permeabilization is required for this application. The use of Leucoperm (Product Code BUF09) is recommended for this purpose.
Source Reference
-
Kraal, .G .et al. (1987) Macrophages in T and B cell compartments and other tissue macrophages recognized by monoclonal antibody MOMA-2. An immunohistochemical study.
Scand J Immunol. 26 (6): 653-61.
References for Macrophages/Monocytes antibody
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Gal, A. et al. (1996) Nitric oxide production in SJL mice bearing the RcsX lymphoma: a model for in vivo toxicological evaluation of NO.
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Fischer, M.B. et al. (1998) Local synthesis of C3 within the splenic lymphoid compartment can reconstitute the impaired immune response in C3-deficient mice.
J Immunol. 160: 2619-25. -
Jiang, H.R. et al. (1999) Macrophages and dendritic cells in IRBP-induced experimental autoimmune uveoretinitis in B10RIII mice.
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Babaei, S. et al. (2000) Blockade of endothelin receptors markedly reduces atherosclerosis in LDL receptor deficient mice: role of endothelin in macrophage foam cell formation.
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Oguchi, S. et al. (2000) Monoclonal antibody against vascular cell adhesion molecule-1 inhibits neointimal formation after periadventitial carotid artery injury in genetically hypercholesterolemic mice.
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Kusunoki, J. et al. (2001) Acyl-CoA:cholesterol acyltransferase inhibition reduces atherosclerosis in apolipoprotein E-deficient mice.
Circulation. 103: 2604-9. -
Lesnik, P. et al. (2003) Decreased atherosclerosis in CX3CR1-/- mice reveals a role for fractalkine in atherogenesis.
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View The Latest Product References
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Frossard, J.L. et al. (2011) Role of CCL-2, CCR-2 and CCR-4 in cerulein-induced acute pancreatitis and pancreatitis-associated lung injury.
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