Ly-6G antibody | 1A8
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Rat anti Mouse Ly-6G
- Product Type
- Monoclonal Antibody
|Rat anti Mouse Ly-6G antibody, clone 1A8 recognizes lymphocyte antigen 6 complex, locus G (Ly-6G).
Ly-6G is a cell surface, glycosylphosphatidylinositol (GPI) anchored protein, expressed on granulocytes in the bone marrow and peripheral blood. Clone 1A8 has been used in vivo in mice to deplete neutrophils (Daley et al. 2008).
- Target Species
- Product Form
- Purified IgG - liquid
- Purified IgG prepared by affinity chromatography
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- <0.1% Sodium Azide (NaN3)
- Ly-6G transfected EL-4J cell line
- Approx. Protein Concentrations
- IgG concentration 0.5 mg/ml
- Fusion Partners
- Spleen cells from immunized LEW/N rats were fused with cells from the murine SP2/0 myeloma.
- For research purposes only
- 12 months from date of despatch
This product should be stored undiluted. Should this product contain a precipitate we recommend microcentrifugation before use.
|Application Name||Verified||Min Dilution||Max Dilution|
- Flow Cytometry
- Use 10ul of the suggested working dilution to label 1x106 cells in 100ul
Fleming, T.J. et al. (1993) Selective expression of Ly-6G on myeloid lineage cells in mouse bone marrow. RB6-8C5 mAb to granulocyte-differentiation antigen (Gr-1) detects members of the Ly-6 family.
J Immunol. 151 (5): 2399-408.
References for Ly-6G antibody
Gabrielli, E. et al. (2018) Saccharomyces cerevisiae-based probiotic as novel anti-fungal and anti-inflammatory agent for therapy of vaginal candidiasis.
Benef Microbes. 9 (2): 219-30.
Rabadi, M.M. et al. (2019) Peptidyl arginine deiminase-4 exacerbates ischemic AKI by finding NEMO (NFκB Essential Modulator).
Am J Physiol Renal Physiol. Apr 03 [Epub ahead of print].
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