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CD31 antibody | ER-MP12

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Anti Mouse CD31 Antibody, clone ER-MP12 thumbnail image 1 Anti Mouse CD31 Antibody, clone ER-MP12 thumbnail image 2 Anti Mouse CD31 Antibody, clone ER-MP12 thumbnail image 3 Anti Mouse CD31 Antibody, clone ER-MP12 thumbnail image 4 Anti Mouse CD31 Antibody, clone ER-MP12 thumbnail image 5 Anti Mouse CD31 Antibody, clone ER-MP12 thumbnail image 6 Anti Mouse CD31 Antibody, clone ER-MP12 thumbnail image 7 Anti Mouse CD31 Antibody, clone ER-MP12 thumbnail image 8
Anti Mouse CD31 Antibody, clone ER-MP12 gallery image 1
Figure A. RPE conjugated rat anti mouse CD45R (MCA1258PE) and FITC conjugated rat IgG2a isotype control (MCA6005F) Figure B. RPE conjugated rat anti mouse CD45R (MCA1258PE) and FITC conjugated rat anti mouse CD31 (MCA2388F). All experiments performed on red cell lysed murine splenocytes gated on mononuclear cells. Data acquired on the ZE5™ cell analyzer.
Anti Mouse CD31 Antibody, clone ER-MP12 gallery image 2
Figure A. Alexa647® conjugated rat anti mouse CD22 (MCA2187A647) and Alexa488® conjugated Rat IgG2a isotype control (MCA1212A488). Figure B. Alexa647® conjugated rat anti mouse CD22 (MCA2187A647) and Alexa488® conjugated rat anti mouse CD31 (MCA2388A488). All experiments performed on red cell lysed murine peripheral blood in the presence of murine SeroBlock (BUF041A).
Anti Mouse CD31 Antibody, clone ER-MP12 gallery image 3
Figure A. RPE conjugated rat anti mouse CD45R (MCA1258PE) and FITC conjugated rat IgG2a isotype control (MCA6005PB) Figure B. RPE conjugated rat anti mouse CD45R (MCA1258PE) and Pacific Blue conjugated rat anti mouse CD31 (MCA2388PB). All experiments performed on red cell lysed murine splenocytes gated on mononuclear cells. Data acquired on the ZE5™ cell analyzer.
Anti Mouse CD31 Antibody, clone ER-MP12 gallery image 4
Immunoperoxidase staining of a mouse lymph node cryosection with Rat anti Mouse CD31 antibody, clone ER-MP12 (MCA2388) followed by horseradish peroxidase conjugated Goat anti Rat IgG antibody (STAR72). Low power
Anti Mouse CD31 Antibody, clone ER-MP12 gallery image 5
Immunoperoxidase staining of a mouse lymph node cryosection with Rat anti Mouse CD31 antibody, clone ER-MP12 (MCA2388) followed by horseradish peroxidase conjugated Goat anti Rat IgG antibody (STAR72). Medium power
Anti Mouse CD31 Antibody, clone ER-MP12 gallery image 6
Immunoperoxidase staining of a mouse lymph node cryosection with Rat anti Mouse CD31 antibody, clone ER-MP12 (MCA2388) followed by horseradish peroxidase conjugated Goat anti Rat IgG antibody (STAR72). High power
Anti Mouse CD31 Antibody, clone ER-MP12 gallery image 7
Published customer image:
Rat anti Mouse CD31 antibody, clone ER-MP12 (MCA2388) used for the detection of blood vessels in an experimental murine tumor model by immunohistofluorescence.
Image caption:
Percentage of pixels positive for NG2 in 4T1 (n = 5) and RM11 (n = 4 and n = 6) tumors (A,D) from WT and β3-KO mice were calculated using immunofluorescent images. No statistical differences in 4T1 (p = 0.90) or RM11 (p = 0.23) were found. Mean ± SD. Representative images of NG2-staining from both genotypes of 4T1 (B,C) (NG2 green, CD31 red) and RM11 (E,F) (NG2 red) tumors are shown. Scale bars indicate 50 μm.

From: Reigstad I, Sortland K, Skogstrand T, Reed RK, Stuhr L.
The Effect of Stromal Integrin β3-Deficiency on Two Different Tumors in Mice.
Cancers (Basel). 2016 Jan 12;8(1). pii: E14.
This image is from an open access article distributed under terms of a Creative Commons Attribution License.
Anti Mouse CD31 Antibody, clone ER-MP12 gallery image 8
Published customer image:
Rat anti Mouse CD31 antibody, clone ER-MP12 (MCA2388) used for the demonstration of vasculature in mouse brain by immunofluorescence.
Image caption:
Inhibition of 2-AG hydrolysis reduces LPS-induced BBB permeability. a, b Fibrinogen levels in b plasma and the a ratio of brain to plasma fibrinogen were assessed by ELISA. n = 5/7 mice per group. c, d Fluorescent immunostaining in the striatum for fibrinogen (red) and vascular marker (CD31; green) demonstrated leakage of fibrinogen into the brain with vehicle treatment, whereas vascular integrity was preserved when (e, f) MAGL was inhibited. g Extravascular fibrinogen was semi-quantitated in fluorescently labeled sections of the striatum. Bar graphs were plotted with mean ±SEM and data analyzed using one-way analysis of variance (ANOVA) with Tukey post-hoc comparisons. n = 5/7 mice per group. Significance is shown as *p <0.05, **p <0.01. Scale bar = 20 μm.

From: Piro JR, Suidan GL, Quan J, Pi Y, O'Neill SM, Ilardi M, Pozdnyakov N, Lanz TA, Xi H, Bell RD, Samad TA.
Inhibition of 2-AG hydrolysis differentially regulates blood brain barrier permeability after injury.
J Neuroinflammation. 2018 May 14;15(1):142.
This image is from an open access article distributed under the terms of a Creative Commons Attribution License.

Rat anti Mouse CD31:Alexa Fluor® 488

Rat anti Mouse CD31:Alexa Fluor® 647

Rat anti Mouse CD31:Biotin

Rat anti Mouse CD31:FITC

Rat anti Mouse CD31:Pacific Blue®

Rat anti Mouse CD31

Rat anti Mouse CD31:RPE

Rat anti Mouse CD31:Alexa Fluor® 700

Product Type
Monoclonal Antibody
Clone
ER-MP12
Isotype
IgG2a
Product Code Applications Pack Size List Price Quantity
MCA2388A488T
Datasheet
F
SDS
25 Tests/0.25ml loader

MCA2388A488
Datasheet
F
SDS
100 Tests/1ml loader

MCA2388A647
Datasheet
F
SDS
100 Tests/1ml loader

MCA2388BT
Datasheet
F
SDS
25 µg loader

MCA2388B
Datasheet
F
SDS
0.1 mg loader

MCA2388F
Datasheet
F
SDS
0.1 mg loader

MCA2388PB
Datasheet
F
SDS
100 Tests/1ml loader

MCA2388T
Datasheet
C* F IF IP
SDS
25 µg loader

MCA2388GA
Datasheet
C* F IF IP
SDS
0.1 mg loader

MCA2388
Datasheet
C* F IF IP
SDS
0.25 mg loader

MCA2388PE
Datasheet
F
SDS
100 Tests loader

MCA2388A700
Datasheet
F
SDS
100 Tests/1ml loader

Rat anti Mouse CD31 antibody, clone ER-MP12 recognizes mouse CD31, a 140 kDa cell surface glycoprotein that is expressed at high levels on endothelial cells, platelets and most leukocyte subpopulations.

CD31 is also expressed on a major population of macrophage / dendritic cell precursors in the bone marrow. Studies show that clone ER-MP12 can be used in conjunction with clone ER-MP20 (MCA2389GA) in two colour flow cytometric analysis, to identify different stages of myeloid progenitor cells in mouse bone marrow (de Bruijn et al. 1998).

Product Details

Target Species
Mouse
Product Form
Purified IgG conjugated to Alexa Fluor®488 - liquid
Product Form
Purified IgG conjugated to Alexa Fluor®647- liquid
Product Form
Purified IgG conjugated to Biotin - liquid
Product Form
Purified IgG conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC) - liquid
Product Form
Purified IgG conjugated to Pacific Blue® - liquid
Product Form
Purified IgG - liquid
Product Form
Purified IgG conjugated to R. Phycoerythrin (RPE) - lyophilized
Product Form
Purified IgG conjugated to Alexa Fluor®700 - liquid
Reconstitution
Reconstitute with 1 ml distilled water
Preparation
Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Preparation
Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Preparation
Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Preparation
Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Preparation
Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Preparation
Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Preparation
Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Preparation
Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Buffer Solution
Phosphate buffered saline
Buffer Solution
Phosphate buffered saline
Buffer Solution
Phosphate buffered saline
Buffer Solution
Phosphate buffered saline
Buffer Solution
Phosphate buffered saline
Buffer Solution
Phosphate buffered saline
Buffer Solution
Phosphate buffered saline
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.09%Sodium Azide
1%Bovine Serum Albumin
Preservative Stabilisers
0.09%Sodium Azide
1%Bovine Serum Albumin
Preservative Stabilisers
0.09%Sodium Azide
1%Bovine Serum Albumin
Preservative Stabilisers
0.09%Sodium Azide
1%Bovine Serum Albumin
Preservative Stabilisers
0.09%Sodium Azide
1%Bovine Serum Albumin
Preservative Stabilisers
0.09%Sodium Azide
Preservative Stabilisers
0.09%Sodium Azide
1%Bovine Serum Albumin
5%Sucrose
Preservative Stabilisers
0.09%Sodium Azide
1%Bovine Serum Albumin
Carrier Free
Yes
Immunogen
BALB/c macrophage precursor cell hybrids
Approx. Protein Concentrations
IgG concentration 0.05 mg/ml
Approx. Protein Concentrations
IgG concentration 0.05 mg/ml
Approx. Protein Concentrations
IgG concentration 0.1 mg/ml
Approx. Protein Concentrations
IgG concentration 0.1 mg/ml
Approx. Protein Concentrations
IgG concentration 0.05 mg/ml
Approx. Protein Concentrations
IgG concentration 1.0 mg/ml
Approx. Protein Concentrations
IgG concentration 0.05 mg/ml
Fusion Partners
Cells from immunised rats were fused with the cells of the rat Y3-Ag1.2.3 myeloma cell line

Storage Information

Storage
Store at +4oC or at -20oC if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. This product is photosensitive and should be protected from light.
Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Storage
Store at +4oC or at -20oC if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. This product is photosensitive and should be protected from light.
Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Storage
Store at +4oC or at -20oC if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Storage
Store at +4oC or at -20oC if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Storage
Store at +4oC or at -20oC if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. This product is photosensitive and should be protected from light.
Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Storage
Store at +4oC or at -20oC if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Storage
Store at +4oC. DO NOT FREEZE.
This product should be stored undiluted. This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use.
Storage
Store at +4oC or at -20oC if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. This product is photosensitive and should be protected from light.
Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Guarantee
12 months from date of despatch
Guarantee
12 months from date of despatch
Guarantee
12 months from date of despatch
Guarantee
12 months from date of despatch
Guarantee
12 months from date of despatch
Guarantee
12 months from date of despatch
Guarantee
12 months from date of despatch
Guarantee
12 months from date of despatch

More Information

UniProt
Q08481
Entrez Gene
Pecam1
GO Terms
GO:0007155 cell adhesion
GO:0016021 integral to membrane
GO:0005625 soluble fraction
GO:0007266 Rho protein signal transduction
GO:0030054 cell junction
GO:0030334 regulation of cell migration
GO:0030485 smooth muscle contractile fiber
GO:0042060 wound healing
GO:0045121 membrane raft
Acknowledgements
This product is provided under an intellectual property licence from Life Technologies Corporation. The transfer of this product is contingent on the buyer using the purchase product solely in research, excluding contract research or any fee for service research, and the buyer must not sell or otherwise transfer this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; (c) manufacturing or quality assurance or quality control, or (d) resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad CA 92008 USA or outlicensing@thermofisher.com
Acknowledgements
This product is provided under an intellectual property licence from Life Technologies Corporation. The transfer of this product is contingent on the buyer using the purchase product solely in research, excluding contract research or any fee for service research, and the buyer must not sell or otherwise transfer this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; (c) manufacturing or quality assurance or quality control, or (d) resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad CA 92008 USA or outlicensing@thermofisher.com
Acknowledgements
This product is provided under an intellectual property licence from Life Technologies Corporation. The transfer of this product is contingent on the buyer using the purchase product solely in research, excluding contract research or any fee for service research, and the buyer must not sell or otherwise transfer this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; (c) manufacturing or quality assurance or quality control, or (d) resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad CA 92008 USA or outlicensing@thermofisher.com
Acknowledgements
This product is provided under an intellectual property licence from Life Technologies Corporation. The transfer of this product is contingent on the buyer using the purchase product solely in research, excluding contract research or any fee for service research, and the buyer must not sell or otherwise transfer this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; (c) manufacturing or quality assurance or quality control, or (d) resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad CA 92008 USA or outlicensing@thermofisher.com
Regulatory
For research purposes only

Applications of CD31 antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Flow Cytometry Neat 1/5
Flow Cytometry Neat 1/10
Flow Cytometry
Flow Cytometry Neat
Flow Cytometry Neat
Flow Cytometry 1/50 Pack Size: 25 µg, 0.25 mg
1/10 Pack Size: 0.1 mg		 1/200 Pack Size: 25 µg, 0.25 mg
1/100 Pack Size: 0.1 mg
Immunofluorescence
Immunohistology - Frozen 1 1/10 1/100
Immunohistology - Paraffin
Immunoprecipitation
Flow Cytometry Neat 1/10
Flow Cytometry Neat
  1. 1The epitope recognised by this antibody is reported to be sensitive to formaldehyde fixation and tissue processing. Bio-Rad recommends the use of acetone fixation for frozen sections.
Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
Flow Cytometry
Use10ul of the suggested working dilution to label 106 cells in 100ul.
Flow Cytometry
Use10ul of the suggested working dilution to label 106 cells in 100ul.
Flow Cytometry
Use10ul of the suggested working dilution to label 106 cells in 100ul.
Flow Cytometry
Use10ul of the suggested working dilution to label 106 cells in 100ul
Flow Cytometry
Use10ul of the suggested working dilution to label 106 cells in 100ul
Flow Cytometry
Use10ul of the suggested working dilution to label 106 cells in 100ul.
Flow Cytometry
Use10ul of the suggested working dilution to label 106 cells in 100ul.
Flow Cytometry
Use10ul of the suggested working dilution to label 106 cells in 100ul
Copyright © 2021 Bio-Rad Antibodies (formerly AbD Serotec)

Secondary Antibodies Available

Description Product Code Applications Pack Size List Price Quantity
Goat anti Rat IgG:Alk. Phos. (Mouse Adsorbed) STAR131A C E P WB 1 ml loader
Goat anti Rat IgG:Biotin (Mouse Adsorbed) STAR131B C E IF P WB 0.5 mg loader
Rabbit F(ab')2 anti Rat IgG:Dylight®800 STAR16D800GA F IF WB 0.1 mg loader
Rabbit F(ab')2 anti Rat IgG:FITC STAR17B F 1 mg loader
Rabbit F(ab')2 anti Rat IgG:HRP STAR21B C E P RE 1 mg loader
Goat F(ab')2 anti Rat IgG:FITC (Mouse Adsorbed) STAR69 F 0.5 ml loader
Goat anti Rat IgG:Dylight®800 (Mouse Adsorbed) STAR71D800GA F IF WB 0.1 mg loader
Goat anti Rat IgG:HRP (Mouse Adsorbed) STAR72 C E P 0.5 mg loader
Goat F(ab')2 anti Rat IgG:RPE (Mouse Adsorbed) STAR73 F 0.5 ml loader

Negative Isotype Controls Available

Description Product Code Applications Pack Size List Price Quantity
Rat IgG2a Negative Control:Alexa Fluor® 488 MCA1212A488 F 100 Tests/1ml loader
Rat IgG2a Negative Control:Alexa Fluor® 647 MCA1212A647 F 100 Tests/1ml loader
Rat IgG2a Negative Control:FITC MCA1212F F 100 Tests loader
Rat IgG2a Negative Control:Pacific Blue® MCA1212PB F 100 Tests/1ml loader
Rat IgG2a Negative Control MCA1212 E F 1 ml loader
Rat IgG2a Negative Control:RPE MCA1212PE F 100 Tests loader
Rat IgG2a Negative Control:Alexa Fluor® 700 MCA1212A700 F 100 Tests/1ml loader

Useful Reagents Available

Description Product Code Applications Pack Size List Price Quantity
Mouse Seroblock FcR BUF041A F 0.1 mg loader
Mouse Seroblock FcR BUF041B F 0.5 mg loader
Mouse Seroblock FcR BUF041A F 0.1 mg loader
Mouse Seroblock FcR BUF041B F 0.5 mg loader
Mouse Seroblock FcR BUF041A F 0.1 mg loader
Mouse Seroblock FcR BUF041B F 0.5 mg loader
Mouse Seroblock FcR BUF041A F 0.1 mg loader
Mouse Seroblock FcR BUF041B F 0.5 mg loader
Mouse Seroblock FcR BUF041A F 0.1 mg loader
Mouse Seroblock FcR BUF041B F 0.5 mg loader
Mouse Seroblock FcR BUF041A F 0.1 mg loader
Mouse Seroblock FcR BUF041B F 0.5 mg loader
Mouse Seroblock FcR BUF041A F 0.1 mg loader
Mouse Seroblock FcR BUF041B F 0.5 mg loader

Application Based External Images

Flow Cytometry

Immunofluorescence

Product Specific References

References for CD31 antibody

  1. Leenen, P.J. et al. (1990) Murine macrophage precursor characterization. II. Monoclonal antibodies against macrophage precursor antigens.
    Eur J Immunol. 20 (1): 27-34.
  2. Wynn, A.A. et al. (2001) Role of granulocyte/macrophage colony-stimulating factor in zymocel-induced hepatic granuloma formation.
    Am J Pathol. 158 (1): 131-45.
  3. de Bruijn, M.F. et al. (1998) Bone marrow cellular composition in Listeria monocytogenes infected mice detected using ER-MP12 and ER-MP20 antibodies: a flow cytometric alternative to differential counting.
    J Immunol Methods. 217 (1-2): 27-39.
  4. Revermann, M. et al. (2010) Soluble epoxide hydrolase deficiency attenuates neointima formation in the femoral cuff model of hyperlipidemic mice.
    Arterioscler Thromb Vasc Biol. 30: 909-14.
  5. Thorp, E. et al. (2011) A reporter for tracking the UPR in vivo reveals patterns of temporal and cellular stress during atherosclerotic progression.
    J Lipid Res. 52 (5): 1033-8.
  6. Thum, T. et al. (2011) Impairment of endothelial progenitor cell function and vascularization capacity by aldosterone in mice and humans.
    Eur Heart J. 32: 1275-86.
  7. Ross, E.A. et al. (2011) CD31 Is Required on CD4+ T Cells To Promote T Cell Survival during Salmonella Infection.
    J Immunol. 187: 1553-65.
  8. Geutskens, S.B. et al. (2005) Macrophages in the murine pancreas and their involvement in fetal endocrine development in vitro.
    J Leukoc Biol. 78: 845-52.
  9. Schledzewski, K. et al. (2011) Deficiency of liver sinusoidal scavenger receptors stabilin-1 and -2 in mice causes glomerulofibrotic nephropathy via impaired hepatic clearance of noxious blood factors.
    J Clin Invest. 121: 703-14.
  10. Sumagin, R. and Sarelius, I.H. (2010) Intercellular adhesion molecule-1 enrichment near tricellular endothelial junctions is preferentially associated with leukocyte transmigration and signals for reorganization of these junctions to accommodate leukocyte passage.
    J Immunol. 184: 5242-52.
  11. Loureiro, J. et al. (2011) Blocking TGF-{beta}1 Protects the Peritoneal Membrane from Dialysate-Induced Damage.
    J Am Soc Nephrol. 22: 1682-95.
  12. Matsakas, A. et al. (2012) Exercise training attenuates the hypermuscular phenotype and restores skeletal muscle function in the myostatin null mouse.
    Exp Physiol. 97 (1): 125-40.
  13. Baumeister, T. et al. (2003) Interleukin-3Ralpha+ myeloid dendritic cells and mast cells develop simultaneously from different bone marrow precursors in cultures with interleukin-3.
    J Invest Dermatol. 121: 280-8.
  14. Moen, I. et al. (2012) Gene expression in tumor cells and stroma in dsRed 4T1 tumors in eGFP-expressing mice with and without enhanced oxygenation.
    BMC Cancer. 12: 21.
  15. Trottier, M.D. et al. (2012) Enhanced production of early lineages of monocytic and granulocytic cells in mice with colitis
    Proc Natl Acad Sci U S A.109: 16594-9.
  16. Ling, V. et al. (1997) Structural identification of the hematopoietic progenitor antigen ER-MP12 as the vascular endothelial adhesion molecule PECAM-1 (CD31).
    Eur J Immunol. 27:509-14.
  17. Nikolic, T. et al. (2002) Developmental stages of myeloid dendritic cells in mouse bone marrow.
    Int Immunol. 15:515-24.
  18. Tagoh, H. et al. (2002) Transcription factor complex formation and chromatin fine structure alterations at the murine c-fms (CSF-1 receptor) locus during maturation of myeloid precursor cells.
    Genes Dev. 16:1721-37.
  19. van Rijt, L. et al. (2002) Allergen-induced accumulation of airway dendritic cells is supported by an increase in CD31(hi)Ly-6C(neg) bone marrow precursors in a mouse model of asthma.
    Blood. 100:3663-71.
  20. van der Loo, J. et al. (1995) Identification of hematopoietic stem cell subsets on the basis of their primitiveness using antibody ER-MP12.
    Blood. 85:952-62.
  21. Fraccarollo, D. et al. (2015) Efficacy of mineralocorticoid receptor antagonism in the acute myocardial infarction phase: eplerenone versus spironolactone
    ESC Heart Failure. 2 (3): 150-8.
  22. Stein-Merlob, A.F. et al. (2015) Blood Accessibility to Fibrin in Venous Thrombosis is Thrombus Age-Dependent and Predicts Fibrinolytic Efficacy: An In Vivo Fibrin Molecular Imaging Study.
    Theranostics. 5 (12): 1317-27.
  23. Yip, H.K. et al. (2016) Tissue plasminogen activator deficiency preserves neurological function and protects against murine acute ischemic stroke.
    Int J Cardiol. 205: 133-41.
  24. Shi, H. et al. (2016) Hiding inside? Intracellular expression of non-glycosylated c-kit protein in cardiac progenitor cells.
    Stem Cell Res. 16 (3): 795-806.
  25. Ono, N. et al. (2014) A subset of chondrogenic cells provides early mesenchymal progenitors in growing bones.
    Nat Cell Biol. 16 (12): 1157-67.
  26. Kroon, P. et al. (2013) JAK-STAT blockade inhibits tumor initiation and clonogenic recovery of prostate cancer stem-like cells.
    Cancer Res. 73 (16): 5288-98.
  27. Trottier MD et al. (2012) Enhancement of hematopoiesis and lymphopoiesis in diet-induced obese mice.
    Proc Natl Acad Sci U S A. 109 (20): 7622-9.
  28. Ryan, T.E. et al. (2016) Mitochondrial therapy improves limb perfusion and myopathy following hindlimb ischemia.
    J Mol Cell Cardiol. 97: 191-6.
  29. Chowdhury, B. et al. (2016) Hyaluronidase 2 (HYAL2) is expressed in endothelial cells, as well as some specialized epithelial cells, and is required for normal hyaluronan catabolism.
    Histochem Cell Biol. 145 (1): 53-66.
  30. Nakamura, Y. et al. (2015) Mesenchymal-stem-cell-derived exosomes accelerate skeletal muscle regeneration.
    FEBS Lett. 589 (11): 1257-65.
  31. Reigstad, I. et al. (2016) The Effect of Stromal Integrin β3-Deficiency on Two Different Tumors in Mice.
    Cancers (Basel). 8 (1): pii: E14.
  32. Cao Y et al. (2016) IL-1β differently stimulates proliferation and multinucleation of distinct mouse bone marrow osteoclast precursor subsets.
    J Leukoc Biol. 100 (3): 513-23.
  33. Bongiorno, E.K. et al. (2017) Type 1 Immune Mechanisms Driven by the Response to Infection with Attenuated Rabies Virus Result in Changes in the Immune Bias of the Tumor Microenvironment and Necrosis of Mouse GL261 Brain Tumors.
    J Immunol. 198 (11): 4513-4523.
  34. Eskilsson, A. et al. (2014) Distribution of microsomal prostaglandin E synthase-1 in the mouse brain.
    J Comp Neurol. 522 (14): 3229-44.
  35. Cao, Y. et al. (2017) TNF-α has both stimulatory and inhibitory effects on mouse monocyte-derived osteoclastogenesis.
    J Cell Physiol. 232 (12): 3273-85.
  36. Piro, J.R. et al. (2018) Inhibition of 2-AG hydrolysis differentially regulates blood brain barrier permeability after injury.
    J Neuroinflammation. 15 (1): 142.

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Watch the Tool Tutorial Video ▸

  • Start by selecting the application you are interested in, with the option to select an instrument from the drop down menu or create a customized instrument
  • Select the fluorophores or fluorescent proteins you want to include in your panel to check compatibility
  • Select the lasers and filters you wish to include
  • Select combined or multi-laser view to visualize the spectra
View more products with CD31 specificity