CD26 antibody | H207-1082

Rat anti Mouse CD26

Product Type
Monoclonal Antibody
Clone
H207-1082
Isotype
IgG2a
Specificity
CD26

Product Code Applications Pack Size List Price Your Price Qty
MCA2345
Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
E F 0.25 mg loader
List Price Your Price
loader
MCA2345GA
Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
E F 0.1 mg loader
List Price Your Price
loader
MCA2345T
Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
E F 25 µg loader
List Price Your Price
loader
Search for Batch Specific Datasheets

Rat anti Mouse CD26 antibody, clone H207-1082 recognizes mouse CD26, which is also known as thymocyte-activating molecule (THAM). Murine CD26 is a type II integral membrane dipeptidyl-peptidase that is expressed at the cell surface as a heterodimer, of approximately 220 kDa, and has a soluble form in the plasma.

The CD26 molecule is a multifunctional glycoprotein that has ectopeptidase activity and is also reported to be involved in cell adhesion, signal transduction in T lymphocytes and HIV infection. CD26 is differentially expressed on developing thymocytes and is upregulated on activated T-cells but is not expressed on resting and thioglycollate stimulated macrophages. Expression of CD26 has also been reported on cells from a variety of non-haematopoietic tissues including liver, intestine and kidney.

Target Species
Mouse
Product Form
Purified IgG - liquid
Preparation
Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.09%Sodium Azide
Carrier Free
Yes
Approx. Protein Concentrations
IgG concentration 1.0 mg/ml
Regulatory
For research purposes only
Guarantee
12 months from date of despatch

This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.

Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
ELISA
Flow Cytometry 1/50 Pack Size: 0.25 mg, 25 µg
1/25 Pack Size: 0.1 mg
1/100
Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
Flow Cytometry
Use 10ul of the suggested working dilution to label 106 cells in 100ul.

Description Product Code Applications Pack Size List Price Your Price Quantity
Goat anti Rat IgG:Alk. Phos. (Mouse Adsorbed) STAR131A C E P WB 1 ml loader
List Price Your Price
loader
Description Goat anti Rat IgG:Alk. Phos. (Mouse Adsorbed)
Goat anti Rat IgG:Biotin (Mouse Adsorbed) STAR131B C E IF P WB 0.5 mg loader
List Price Your Price
loader
Description Goat anti Rat IgG:Biotin (Mouse Adsorbed)
Rabbit F(ab')2 anti Rat IgG:Dylight®800 STAR16D800GA F IF WB 0.1 mg loader
List Price Your Price
loader
Description Rabbit F(ab')2 anti Rat IgG:Dylight®800
Rabbit F(ab')2 anti Rat IgG:FITC STAR17B F 1 mg loader
List Price Your Price
loader
Description Rabbit F(ab')2 anti Rat IgG:FITC
Rabbit F(ab')2 anti Rat IgG:HRP STAR21B C E P RE 1 mg loader
List Price Your Price
loader
Description Rabbit F(ab')2 anti Rat IgG:HRP
Goat F(ab')2 anti Rat IgG:FITC (Mouse Adsorbed) STAR69 F 0.5 ml loader
List Price Your Price
loader
Description Goat F(ab')2 anti Rat IgG:FITC (Mouse Adsorbed)
Goat anti Rat IgG:Dylight®800 (Mouse Adsorbed) STAR71D800GA F IF WB 0.1 mg loader
List Price Your Price
loader
Description Goat anti Rat IgG:Dylight®800 (Mouse Adsorbed)
Goat anti Rat IgG:HRP (Mouse Adsorbed) STAR72 C E P 0.5 mg loader
List Price Your Price
loader
Description Goat anti Rat IgG:HRP (Mouse Adsorbed)
Goat F(ab')2 anti Rat IgG:RPE (Mouse Adsorbed) STAR73 F 0.5 ml loader
List Price Your Price
loader
Description Goat F(ab')2 anti Rat IgG:RPE (Mouse Adsorbed)

Description Product Code Applications Pack Size List Price Your Price Quantity
Rat IgG2a Negative Control MCA1212 E F 1 ml loader
List Price Your Price
loader
Description Rat IgG2a Negative Control

References for CD26 antibody

  1. David, F. et al. (1993) Identification of serine 624, aspartic acid 702, and histidine 734 as the catalytic triad residues of mouse dipeptidyl-peptidase IV (CD26). A member of a novel family of nonclassical serine hydrolases.
    J Biol Chem. 268:17247-52.
  2. Marguet, D. et al. (2000) Enhanced insulin secretion and improved glucose tolerance in mice lacking CD26.
    Proc Natl Acad Sci U S A. 97:6874-9.

Further Reading

  1. Vivier, I. et al. (1991) Evidence that thymocyte-activating molecule is mouse CD26 (dipeptidyl peptidase IV).
    J Immunol. 147 (2): 447-54.

Synonyms
THAM
RRID
AB_566676
UniProt
P28843
Entrez Gene
Dpp4
GO Terms
GO:0002020 protease binding
GO:0004252 serine-type endopeptidase activity
GO:0004177 aminopeptidase activity
GO:0008239 dipeptidyl-peptidase activity
GO:0005102 receptor binding
GO:0007155 cell adhesion
GO:0016021 integral to membrane
GO:0005576 extracellular region
GO:0004872 receptor activity
GO:0030139 endocytic vesicle
GO:0006508 proteolysis
GO:0008284 positive regulation of cell proliferation
GO:0009986 cell surface
GO:0010716 negative regulation of extracellular matrix disassembly
GO:0016324 apical plasma membrane
GO:0031258 lamellipodium membrane
GO:0031295 T cell costimulation
GO:0042803 protein homodimerization activity
GO:0043542 endothelial cell migration
GO:0045121 membrane raft
GO:0046581 intercellular canaliculus
GO:0071438 invadopodium membrane
View more products with CD26 specificity

Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

View all Anti-Mouse Products