Rat anti Mouse CD202b antibody, clone TEK4
recognizes mouse CD202, also known as TIE-2 or TEK, a protein-tyrosine kinase transmembrane receptor for angiopoietin 1. CD202b is expressed in developing vascular endothelial cells and probably regulates endothelial cell proliferation and differentiation and guides the proper patterning of endothelial cells during blood vessel formation. Defects in the gene are associated with venous malformations (Sato et al. 1995
- Target Species
- Product Form
- Purified IgG - liquid
- Purified IgG prepared by affinity chromatography
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3)
- Approx. Protein Concentrations
- IgG concentration 0.5mg/ml
- Store at +4oC or at -20oC if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
- 18 months from date of despatch.
- Entrez Gene
- GO Terms
transmembrane receptor protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase signaling pathway
integral to plasma membrane
regulation of cell migration
response to retinoic acid
positive regulation of peptidyl-serine phosphorylation
regulation of angiogenesis
positive regulation of cell adhesion
- For research purposes only
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Applications of CD202b antibody
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
- Flow Cytometry
- Use 10ul of the suggested working dilution to label 1x106 cells in 100ul.
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Secondary Antibodies Available