CD150 antibody | 9D1
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|Rat anti Mouse CD150 antibody, clone 9D1 recognizes murine CD150, also known as signaling lymphocyte activation molecule (SLAM) . Murine CD150 is a 75 kDa cell surface glycoprotein that is expressed on T-cells and B-cells, and is upregulated on activated T-cells and stimulated macrophages. The extracellular domain of CD150 is the receptor for the measles virus (Erlenhoefer et al. 2001) and acts as a co-activator on T-cells and B-cells.
Rat anti Mouse CD150 antibody, clone 9D1 has functional activity (Howie et al. 2002).
- Target Species
- Product Form
- Purified IgG - liquid
- Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
0.09% Sodium Azide
- Carrier Free
- CHO cells stably transfected with mouse CD150
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
- Fusion Partners
- Spleen cells from immunised rats were fused with cells of a myeloma cell line.
- For research purposes only
- 12 months from date of despatch
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
|Application Name||Verified||Min Dilution||Max Dilution|
- Flow Cytometry
- Use 10ul of the suggested working dilution to label 106 cells in 100ul
References for CD150 antibody
Howie, D. et al. (2002) The role of SAP in murine CD150 (SLAM)-mediated T-cell proliferation and interferon gamma production.
Blood. 100 (8): 2899-907.
Desponts, C. et al. (2006) SHIP deficiency enhances HSC proliferation and survival but compromises homing and repopulation.
Blood. 107: 4338-45.
Almolda, B. et al. (2015) Alterations in microglial phenotype and hippocampal neuronal function in transgenic mice with astrocyte-targeted production of interleukin-10.
Brain Behav Immun. 45: 80-97.
Villacampa, N. et al. (2015) Astrocyte-targeted production of IL-10 induces changes in microglial reactivity and reduces motor neuron death after facial nerve axotomy.
Glia. 63 (7): 1166-84.
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