SARS-CoV-2 Spike Protein S1 antibody

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Rabbit anti SARS-CoV-2 Spike Protein S1

Product Type
Polyclonal Antibody
Product Code Applications Pack Size List Price Quantity
0.1 mg loader

Rabbit anti SARS-CoV-2 spike protein S1 antibody recognizes spike glycoprotein S1, also known as S glycoprotein, peplomer protein and E2.

Human coronaviruses are pathogens that can cause severe respiratory tract infections. SARS-CoV-2 is a novel human coronavirus characterized in 2020, and causes "coronavirus disease 2019" or "COVID-19" (Xu et al. 2020). The spike glycoproteins of coronaviruses are incorporated into the viral envelope and promote entry into cells (Walls et al. 2020). The spike glycoprotein of SARS-CoV-2 is comprised of two subunits called S1 and S2. The S1 protein binds to a receptor on human cells, and the transmembrane unit S2 helps fuse the viral membrane with a cellular membrane (Hoffmann et al. 2020). Specifically, both SARS-CoV and SARS-CoV-2 spike proteins contain a receptor-binding domain (RBD) that recognize the same receptor, ACE2, on human cells (Shang et al. 2020). This antibody recognizes the spike S1 protein of SARS-CoV-2.

Product Details

Target Species
Product Form
Purified IgG - liquid
Rabbit polyclonal antibody purified by affinity chromatography
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.02% Sodium Azide (NaN3)
Peptide corresponding to 16 amino acids near the amino terminus of SARS-CoV-2 (COVID-19) Spike S1 glycoprotein.

The immunogen is located within the first 50 amino acids of SARS-CoV-2 (COVID-19) Spike S1 protein.
Approx. Protein Concentrations
1.0 mg/ml

Storage Information

This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.

Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
12 months from date of despatch

More Information

For research purposes only

Applications of SARS-CoV-2 Spike Protein S1 antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
ELISA 1000 ng/ml 8 ng/ml
Immunocytochemistry 5 ug/ml
Immunohistology - Paraffin 0.5 ug/ml
Western Blotting 1 ug/ml
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.

Secondary Antibodies Available

Description Product Code Applications Pack Size List Price Quantity
Goat anti Rabbit IgG (Fc):Biotin STAR121B E WB 1 mg loader
Goat anti Rabbit IgG (Fc):FITC STAR121F F 1 mg loader
Goat anti Rabbit IgG (Fc):HRP STAR121P E WB 1 mg loader
Goat anti Rabbit IgG (H/L):HRP STAR124P C E WB 1 mg loader
Sheep anti Rabbit IgG:FITC STAR34B C F 1 mg loader
Sheep anti Rabbit IgG:RPE STAR35A F 1 ml loader

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