Calcitonin Receptor antibody

Rabbit anti Rat Calcitonin Receptor

Product Type
Polyclonal Antibody
Isotype
Polyclonal IgG
Specificity
Calcitonin Receptor

Product Code Applications Pack Size List Price Your Price Qty
New AHP3115
Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
C E IC WB 0.1 mg
List Price Your Price

Rabbit anti rat calcitonin receptor antibody recognizes rat calcitonin receptor, also known as CT-R or C1A/C1B.

Calcitonin receptor is a seven-transmembrane domain G protein-coupled receptor that binds the protein hormone calcitonin. It is expressed in kidneys, central and peripheral nervous system, skeletal muscle stem cells and osteocytes. Investigations on calcitonin receptor’s function have mainly focused on its role in regulating calcium homeostasis and osteoclast-mediated bone resorption. However, a growing body of evidence suggests that calcitonin receptor could also be involved in foetal morphogenesis and cancer development.

Rabbit anti rat calcitonin receptor antibody binds to an intracellular epitope of the calcitonin receptor that is shared by both C1a and C1b rat calcitonin receptor isoforms. It has been shown to cross-react with mouse calcitonin receptor.

Target Species
Rat
Species Cross-Reactivity
Target SpeciesCross Reactivity
Mouse
Human Weak
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Purified IgG - lyophilized
Reconstitution
Reconstitute with 100ul distilled water
Antiserum Preparation
Antisera to calcitonin receptor were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography on Protein A.
Buffer Solution
10 mM Sodium Phosphate
Preservative Stabilisers
0.01% Sodium Azide (NaN3)
Immunogen
Synthetic peptide derived from a C-terminal sequence of rat calcitonin receptor.
Approx. Protein Concentrations
IgG concentration 1.0 mg/ml after reconstitution
Regulatory
For research purposes only
Guarantee
12 months from date of despatch

Prior to reconstitution store at +4°C.
After reconstitution store at -20°C.
Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
ELISA 1/20,000
Immunocytochemistry 1/1,000
Immunohistology - Frozen 1/1,000 1/5,000
Western Blotting
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
Histology Positive Control Tissue
Kidney, cultured osteoclasts

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UniProt
P32214
Entrez Gene
Calcr
GO Terms
GO:0005886 plasma membrane
GO:0016021 integral to membrane
GO:0004948 calcitonin receptor activity
GO:0030424 axon
GO:0032841 calcitonin binding
GO:0043025 neuronal cell body

AHP3115

164178

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View more products with CALCITONIN RECEPTOR specificity

Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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