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TDG antibody

Rabbit anti Mouse TDG

Product Type
Polyclonal Antibody
Isotype
Polyclonal IgG
Specificity
TDG

Product Code Applications Pack Size List Price Your Price Qty
AHP3109
Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
WB 0.1 ml loader
List Price Your Price
loader

Rabbit anti Mouse TDG antibody recognizes G/T mismatch-specific thymine DNA glycosylase.

TDG is a member of the TDG/mug DNA glycosylase family and predominantly removes thymine residues from sites where G/T mismatches have occurred. TDG can also remove thymine from C/T and T/T mispairings and uracil and 5-bromouracil from mispairings with guanine (Gallinari and Jiricny, 1996). TDG may also play a role in 5-methylcytosine demethylation in mammalian cells (Zhang et al. 2012).

Target Species
Mouse
Product Form
Purified IgG - liquid
Antiserum Preparation
Antiserum to mouse TDG was raised by repeated immunization of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography on Protein A.
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.035% Sodium Azide (NaN3)
30% Glycerol
Carrier Free
Yes
Immunogen
A full-length recombinant protein corresponding to mouse TDG
Regulatory
For research purposes only
Guarantee
12 months from date of despatch

This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.

Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/500 1/1500
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.

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UniProt
P56581
Entrez Gene
Tdg
GO Terms
GO:0005634 nucleus
GO:0006298 mismatch repair
GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds
GO:0030983 mismatched DNA binding

AHP3109

160776

If you cannot find the batch/lot you are looking for please contact our technical support team for assistance.

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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

View all Anti-Mouse Products
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