NANOG antibody
Rabbit anti Mouse NANOG
- Product Type
- Polyclonal Antibody
- Isotype
- Polyclonal IgG
- Specificity
- NANOG
Rabbit anti Mouse NANOG antibody recognizes homeobox protein NANOG, otherwise known as homeobox transcription factor NANOG. NANOG plays a role in the proliferation and self-renewal of embryonic stem (ES) cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages (Barral et al. 2019). Overexpression of NANOG has been shown to promote cells to enter into S phase and proliferation (Sainz de Aja et al. 2019). |
- Target Species
- Mouse
- Species Cross-Reactivity
-
Target Species Cross Reactivity Human - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Antiserum Preparation
- Antiserum to mouse NANOG was raised by repeated immunization of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.035% Sodium Azide (NaN3)
30% Glycerol - Carrier Free
- Yes
- Immunogen
- A peptide within the N-terminal region of mouse NANOG
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use.
Application Name | Verified | Min Dilution | Max Dilution |
---|---|---|---|
Chromatin Immunoprecipitation | 5 µl per ChIP | ||
Immunofluorescence | 1/200 | ||
Western Blotting | 0.5 µg/ml | 2 µg/ml |
Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
---|---|---|---|---|---|---|---|
Goat anti Rabbit IgG (Fc):Biotin | STAR121B | E WB | 1 mg | Log in | |||
List Price | Your Price | ||||||
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Description | Goat anti Rabbit IgG (Fc):Biotin | ||||||
Goat anti Rabbit IgG (Fc):FITC | STAR121F | F | 1 mg | Log in | |||
List Price | Your Price | ||||||
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Description | Goat anti Rabbit IgG (Fc):FITC | ||||||
Goat anti Rabbit IgG (Fc):HRP | STAR121P | E WB | 1 mg | Log in | |||
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Description | Goat anti Rabbit IgG (Fc):HRP | ||||||
Goat anti Rabbit IgG (H/L):HRP | STAR124P | C E WB | 1 mg | Log in | |||
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Description | Goat anti Rabbit IgG (H/L):HRP | ||||||
Sheep anti Rabbit IgG:RPE | STAR35A | F | 1 ml | Log in | |||
List Price | Your Price | ||||||
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Description | Sheep anti Rabbit IgG:RPE |
- UniProt
- Q80Z64
- Entrez Gene
- Nanog
- GO Terms
- GO:0000122 negative regulation of transcription from RNA polymerase II promoter
- GO:0005515 protein binding
- GO:0001710 mesodermal cell fate commitment
- GO:0003700 sequence-specific DNA binding transcription factor activity
- GO:0005634 nucleus
- GO:0009880 embryonic pattern specification
- GO:0008284 positive regulation of cell proliferation
- GO:0008406 gonad development
- GO:0017145 stem cell division
- View More GO Terms
- GO:0019827 stem cell maintenance
- GO:0030514 negative regulation of BMP signaling pathway
- GO:0030528 transcription regulator activity
- GO:0032526 response to retinoic acid
- GO:0042664 negative regulation of endodermal cell fate specification
- GO:0043565 sequence-specific DNA binding
- GO:0045931 positive regulation of mitotic cell cycle
AHP3085
160778If you cannot find the batch/lot you are looking for please contact our technical support team for assistance.
Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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