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LSD2 antibody

Rabbit anti Mouse LSD2

Product Type
Polyclonal Antibody
Isotype
Polyclonal IgG
Specificity
LSD2

Product Code Applications Pack Size List Price Your Price Qty
AHP3080
Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
WB 0.1 ml loader
List Price Your Price
loader

Rabbit anti Mouse LSD2 antibody recognizes lysine (K)-specific demethylase 1B, also known as KDM1B.

LSD2 is a flavin-dependent histone demethylase enzyme. Flavin-dependent histone demethylase enzymes mediate histone lysine methylation, thereby regulating gene expression and chromatin function (Karytinos et al. 2009).

Target Species
Mouse
Product Form
Purified IgG - liquid
Antiserum Preparation
Antiserum to mouse LSD2 was raised by repeated immunization of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.035% Sodium Azide (NaN3)
30% Glycerol
Carrier Free
Yes
Immunogen
A peptide within the N-terminal region of mouse LSD2
Regulatory
For research purposes only
Guarantee
12 months from date of despatch

This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.

Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/500 1/2000
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.

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Synonyms
Lysine-Specific Histone Demethylase 1B
UniProt
Q8CIG3
Entrez Gene
Kdm1b
GO Terms
GO:0005634 nucleus
GO:0055114 oxidation-reduction process
GO:0016491 oxidoreductase activity
GO:0006349 regulation of gene expression by genetic imprinting
GO:0006350 transcription
GO:0007275 multicellular organismal development
GO:0008270 zinc ion binding
GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)
GO:0034649 histone demethylase activity (H3-monomethyl-K4 specific)
GO:0043046 DNA methylation involved in gamete generation
GO:0044030 regulation of DNA methylation
GO:0045449 regulation of transcription
GO:0050660 flavin adenine dinucleotide binding

AHP3080

160771

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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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