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MBP antibody

Product Code Applications Pack Size List Price Your Price Qty
0300-0082
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SDS Safety Datasheet SDS
E IF WB 1 ml loader
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loader

Rabbit anti Human MBP antibody recognizes human myelin basic protein (MBP), an abundant protein component of the myelin membrane and is reported to have a role in its formation and stabilisation.

Target Species
Human
Species Cross-Reactivity
Target SpeciesCross Reactivity
Rat
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Purified IgG - liquid
Preparation
Purified IgG prepared by affinity chromatography on Protein G
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.09% Sodium Azide (NaN3)
Immunogen
Native myelin basic protein from human brain.
Approx. Protein Concentrations
IgG concentration 1.0 mg/ml
Regulatory
For research purposes only
Guarantee
12 months from date of despatch

This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.

Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
ELISA 1/100 1/400
Immunofluorescence
Western Blotting
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using the appropriate negative/positive controls.
Western Blotting
0300-0082 detects band at 18.5 kDa on reducing SDS-PAGE against rat brain lysate.

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References for MBP antibody

  1. Seiberlich, V. et al. (2015) Downregulation of the microtubule associated protein Tau impairs process outgrowth and myelin basic protein mRNA transport in oligodendrocytes.
    Glia. 63 (9): 1621-35.
  2. Krajnak, K. et al. (2016) Long-term daily vibration exposure alters current perception threshold (CPT) sensitivity and myelinated axons in a rat-tail model of vibration-induced injury.
    J Toxicol Environ Health A. 79 (3): 101-11.
  3. Garinis, G. et al. (2021) DNA damage in tissue-resident macrophages leads to age-related neurodegeneration
    Res Sq. Dec 01 [Epub ahead of print].
  4. Chaudhary, P. et al. (2022) Optic Nerve Head Myelin-Related Protein, GFAP, and Iba1 Alterations in Non-Human Primates With Early to Moderate Experimental Glaucoma.
    Invest Ophthalmol Vis Sci. 63 (11): 9.

Synonyms
Myelin Basic Protein
RRID
AB_2250337
UniProt
P02686
Entrez Gene
MBP

0300-0082

1114 166479

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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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