CD103 antibody | 2E7
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Hamster anti Mouse CD103
- Product Type
- Monoclonal Antibody
- Clone
- 2E7
- Isotype
- IgG
- Specificity
- CD103
Antibody Quality and Performance Guarantee
| Hamster anti Mouse CD103 antibody, clone 2E7 recognizes mouse CD103, otherwise known as integrin alpha-E. CD103 binds Integrin beta 7 to form the heterodimeric integrin molecule αEβ7. This complex is sometimes referred to as CD103, though strictly speaking CD103 only refers to the alpha chain. The beta 7 subunit can also interact with other integrin alpha chains. The αEβ7 complex is a receptor for E-cadherin. It mediates adhesion of intra-epithelial T-lymphocyes to epithelial cell monolayers. CD103 is expressed on intestinal intraepithelial lymphocytes and is highly expressed on regulatory T cells. Hamster anti Mouse CD103 antibody, clone 2E7 is expected to also recognize the intact αEβ7 complex. |
- Target Species
- Mouse
- Product Form
- Purified IgG - liquid
- Preparation
- Purified IgG prepared by affinity chromatography
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- <0.1% Sodium Azide (NaN3)
- Immunogen
- Mouse intestinal intraepithelial lymphocytes
- Approx. Protein Concentrations
- IgG concentration 0.5mg/ml
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Flow Cytometry |  |
1/10 | 1/20 |
| Immunofluorescence | |
||
| Immunohistology - Frozen | |
||
| Immunoprecipitation | |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
- Flow Cytometry
- Use 10ul of the suggested working dilution to label 1x106 cells in 100ul.
| Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
|---|---|---|---|---|---|---|---|
| Goat F(ab')2 anti Hamster IgG:Dylight®800 | STAR104D800GA | F IF WB | 0.1 mg |
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| Description | Goat F(ab')2 anti Hamster IgG:Dylight®800 | ||||||
| Goat F(ab')2 anti Hamster IgG:FITC | STAR104F | F | 0.4 mg |
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| Description | Goat F(ab')2 anti Hamster IgG:FITC | ||||||
| Goat anti Hamster IgG:Biotin | STAR79B | E F | 0.8 mg |
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| Description | Goat anti Hamster IgG:Biotin | ||||||
| Goat anti Hamster IgG:FITC | STAR79F | F | 0.7 mg |
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| Description | Goat anti Hamster IgG:FITC | ||||||
| Goat anti Hamster IgG:HRP | STAR79P | E | 0.8 mg |
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| Description | Goat anti Hamster IgG:HRP | ||||||
| Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
|---|---|---|---|---|---|---|---|
| Hamster (Armenian) IgG Negative Control | MCA2356 | F | 0.25 mg |
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| Description | Hamster (Armenian) IgG Negative Control | ||||||
References for CD103 antibody
-
Lefrançois, L. et al. (1994) Developmental expression of the alpha IEL beta 7 integrin on T cell receptor gamma delta and T cell receptor alpha beta T cells.
Eur J Immunol. 24: 635- 640
- RRID
- AB_2249322
- UniProt
- Q60677
- Entrez Gene
- Itgae
- GO Terms
- GO:0007155 cell adhesion
- GO:0004872 receptor activity
- GO:0008305 integrin complex
- GO:0007229 integrin-mediated signaling pathway
- GO:0009897 external side of plasma membrane
MCA4705GA
155436
180412
If you cannot find the batch/lot you are looking for please contact our technical support team for assistance.
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