Endothelin antibody | 3G10

Product Details
- Target Species
- Human
- Product Form
- Purified IgG - liquid
- Preparation
- Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
0.1% Sodium Azide (NaN3) - Immunogen
- Synthetic peptide corresponding to the c-terminal region of human endothelin (CHLDIIW) conjugated to BSA.
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
Storage Information
- Storage
- Store at +4oC or at -20oC if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted.
Avoid repeated freezing and thawing as this may denature the antibody.
Should this product contain a precipitate we recommend microcentrifugation before use. - Guarantee
- 12 months from date of despatch
More Information
- UniProt
- P05305
- P14138
- P20800
- Entrez Gene
- EDN1
- EDN3
- EDN2
- GO Terms
- GO:0001516 prostaglandin biosynthetic process
- GO:0003100 regulation of systemic arterial blood pressure by endothelin
- GO:0005179 hormone activity
- GO:0005615 extracellular space
- GO:0005737 cytoplasm
- GO:0019722 calcium-mediated signaling
- GO:0010460 positive regulation of heart rate
- GO:0010595 positive regulation of endothelial cell migration
- GO:0010613 positive regulation of cardiac muscle hypertrophy
- GO:0014065 phosphatidylinositol 3-kinase cascade
- GO:0014824 artery smooth muscle contraction
- GO:0014826 vein smooth muscle contraction
- GO:0046887 positive regulation of hormone secretion
- GO:0019229 regulation of vasoconstriction
- GO:0030072 peptide hormone secretion
- GO:0030185 nitric oxide transport
- GO:0030195 negative regulation of blood coagulation
- GO:0031707 endothelin A receptor binding
- GO:0031708 endothelin B receptor binding
- GO:0042313 protein kinase C deactivation
- GO:0043507 positive regulation of JUN kinase activity
- GO:0045321 leukocyte activation
- GO:0045429 positive regulation of nitric oxide biosynthetic process
- GO:0045793 positive regulation of cell size
- GO:0045840 positive regulation of mitosis
- GO:0048661 positive regulation of smooth muscle cell proliferation
- GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process
- GO:0060298 positive regulation of sarcomere organization
- GO:0060585 positive regulation of prostaglandin-endoperoxide synthase activity
- GO:0002690 positive regulation of leukocyte chemotaxis
- GO:0005625 soluble fraction
- GO:0007166 cell surface receptor linked signaling pathway
- GO:0048016 inositol phosphate-mediated signaling
- GO:0030593 neutrophil chemotaxis
- GO:0043406 positive regulation of MAP kinase activity
- GO:0003058 hormonal regulation of the force of heart contraction
- GO:0003099 positive regulation of the force of heart contraction by chemical signal
- GO:0007204 elevation of cytosolic calcium ion concentration
- GO:0008284 positive regulation of cell proliferation
- GO:0019221 cytokine-mediated signaling pathway
- GO:0042116 macrophage activation
- GO:0048246 macrophage chemotaxis
- Regulatory
- For research purposes only
Applications of Endothelin antibody
Application Name | Verified | Min Dilution | Max Dilution |
---|---|---|---|
Immunohistology - Frozen 1 | |||
IRMA |
- 1Frozen sections processed with dry acetone are recommended. Paraformaldehyde is not recommended as it destroys the epitope.
- Immunohistology
- Frozen sections processed with dry acetone are recommended. Paraformaldehyde is not recommended as it destroys the epitope.
Secondary Antibodies Available
Description | Product Code | Applications | Pack Size | List Price | Quantity |
---|---|---|---|---|---|
Goat anti Rat IgG:Alk. Phos. (Mouse Adsorbed) | STAR131A | C E P WB | 1 ml |
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|
Goat anti Rat IgG:Biotin (Mouse Adsorbed) | STAR131B | C E IF P WB | 0.5 mg |
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|
Rabbit F(ab')2 anti Rat IgG:Dylight®800 | STAR16D800GA | F IF WB | 0.1 mg |
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|
Rabbit F(ab')2 anti Rat IgG:FITC | STAR17B | F | 1 mg |
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|
Rabbit F(ab')2 anti Rat IgG:HRP | STAR21B | C E P RE | 1 mg |
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|
Goat F(ab')2 anti Rat IgG:FITC (Mouse Adsorbed) | STAR69 | F | 0.5 ml |
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|
Goat anti Rat IgG:Dylight®800 (Mouse Adsorbed) | STAR71D800GA | F IF WB | 0.1 mg |
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|
Goat anti Rat IgG:HRP (Mouse Adsorbed) | STAR72 | C E P | 0.5 mg |
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|
Goat F(ab')2 anti Rat IgG:RPE (Mouse Adsorbed) | STAR73 | F | 0.5 ml |
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Product Specific References
References for Endothelin antibody
-
Yao, J. et al. (2001) Endothelin is a potent inhibitor of matrix metalloproteinase-2 secretion and
activation in rat mesangial cells.
Am J Physiol Renal Physiol. 280: F628-635.
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