CD235a antibody | YTH89.1
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Rat anti Human CD235a
- Product Type
- Monoclonal Antibody
|Rat anti Human CD235a antibody, clone YTH89.1 recognizes glycophorin A, a major sialoglycoprotein of the human erythrocyte membrane.|
- Target Species
- Product Form
- Purified IgG - liquid
- Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
0.09% Sodium Azide
- Carrier Free
- Approx. Protein Concentrations
- IgG concentration 1 mg/ml
- Fusion Partners
- Spleen cells from immunized DA rats were fused with cells of the Y3/Ag.1.2.3.
- For research purposes only
- 12 months from date of despatch
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
|Application Name||Verified||Min Dilution||Max Dilution|
|Immunohistology - Frozen||1/100||1/1000|
|Immunohistology - Paraffin||1/100||1/1000|
- This product does not require antigen retrieval using heat treatment prior to staining of paraffin sections.
- Histology Positive Control Tissue
- Human hypophysis
References for CD235a antibody
Outram, S. et al. (1988) Erythromyeloid lineage fidelity is conserved in erythroleukaemia.
Leuk Res. 12 (8): 651-7.
Jokiranta, T.S. & Meri, S. (1993) Biotinylation of monoclonal antibodies prevents their ability to activate the classical pathway of complement.
J Immunol. 151 (4): 2124-31.
(2010) Erythrocyte membrane defects and asymmetry in paroxysmal nocturnal hemoglobinuria and myelodysplastic syndrome.
Hematology. 15: 236-9.
Hoang, T. et al. (1996) Opposing effects of the basic helix-loop-helix transcription factor SCL on erythroid and monocytic differentiation.
Blood. 87: 102-11.
Lahlil, R. et al. (2004) SCL assembles a multifactorial complex that determines glycophorin A expression.
Mol Cell Biol. 24: 1439-52.
Tiziani, S. et al. (2009) Metabolomic profiling of drug responses in acute myeloid leukaemia cell lines.
PLoS One. 2009;4(1):e4251.
Saha, S. et al. (2011) Elevated levels of redox regulators, membrane-bound globin chains, and cytoskeletal protein fragments in hereditary spherocytosis erythrocyte proteome.
Eur J Haematol. 87: 259-66.
Challier, J.C. et al. (2005) Immunocytological evidence for hematopoiesis in the early human placenta.
Placenta. 26: 282-8.
View The Latest Product References
Huang, Y.C. et al. (2009) Oral small-molecule tyrosine kinase inhibitor midostaurin (PKC412) inhibits growth and induces megakaryocytic differentiation in human leukemia cells.
Toxicol In Vitro. 23: 979-85.
Lucky AB et al. (2016) Plasmodium knowlesi Skeleton-Binding Protein 1 Localizes to the 'Sinton and Mulligan' Stipplings in the Cytoplasm of Monkey and Human Erythrocytes.
PLoS One. 11 (10): e0164272.
Babiker, A.A. et al. (2002) Transfer of prostasomal CD59 to CD59-deficient red blood cells results in protection against complement-mediated hemolysis.
Am J Reprod Immunol. 47 (3): 183-92.
Scanlon, V.M. et al. (2022) Multiparameter analysis of timelapse imaging reveals kinetics of megakaryocytic erythroid progenitor clonal expansion and differentiation.
Sci Rep. 12 (1): 16218.
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