MBP antibody | 12
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|Rat anti MBP antibody, clone 12 recognizes myelin basic protein from a wide range of species. Rat anti MBP antibody, clone 12 reacts weakly with peptides ending in the Phe 91 where the 91-92 Phe-Phe bond is broken. Synthetic peptide 82-99 reacts very well with Rat anti MBP antibody, clone 12, as does intact MBP. Further epitope analysis indicates binding to a region defined by amino acids 82-87 (DENPVV).
Rat anti MBP antibody, clone 12 has been reported as being suitable for use in western blotting (Glynn et al. 1987).
- Target Species
- Species Cross-Reactivity
Target Species Cross Reactivity Mouse Rabbit Mammals Expected from Sequence Rat Guinea Pig Sheep Human Chicken Pig
- N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Tissue Culture Supernatant - liquid
- Buffer Solution
- 0.1M TRIS
- Preservative Stabilisers
0.1% Sodium Azide
- Bovine MBP.
- Fusion Partners
- Spleen cells from an immunised outbred rat were fused with cells of the mouse NS0 myeloma cell line.
- For research purposes only
- 12 months from date of despatch
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
|Application Name||Verified||Min Dilution||Max Dilution|
References for MBP antibody
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Pohl, H.B. et al. (2011) Genetically induced adult oligodendrocyte cell death is associated with poor myelin clearance, reduced remyelination, and axonal damage.
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Laursen, L.S. et al. (2011) Translation of myelin basic protein mRNA in oligodendrocytes is regulated by integrin activation and hnRNP-K.
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Relucio, J. et al. (2009) Laminin alters fyn regulatory mechanisms and promotes oligodendrocyte development.
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Savvaki, M. et al. (2010) The expression of TAG-1 in glial cells is sufficient for the formation of the juxtaparanodal complex and the phenotypic rescue of tag-1 homozygous mutants in the CNS.
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View The Latest Product References
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