MHC Class II antibody | PF6J-6D
Mouse anti Cat MHC Class II
- Product Type
- Monoclonal Antibody
- Clone
- PF6J-6D
- Isotype
- IgG2b
- Specificity
- MHC Class II
Mouse anti Cat MHC Class II antibody, clone PF6J-6D recognizes an epitope within the ~29-31 kDa beta chain region of cat MHC class II molecules which are expressed by antigen presenting cells, B cells, monocytes and activated T lymphocytes. The major histocompatibility complex (MHC) is a cluster of genes that are important in the immune response to infections. In cats, this is referred to as the feline leukocyte antigen (FLA) region. The complex retrovirus FIV (feline immunodeficiency virus), is responsible for a progressive and debilitating immune deficiency syndrome in domestic cats, similar to that caused by the human Immunodeficiency virus (HIV), the intensity of MHC Class II expression on cat lymphocyte membranes has been found to vary in association with feline retrovirus infections. |
- Target Species
- Cat
- Product Form
- Purified IgG - liquid
- Preparation
- Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- <0.1% Sodium Azide (NaN3)
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
Application Name | Verified | Min Dilution | Max Dilution |
---|---|---|---|
ELISA | |||
Flow Cytometry | |||
Immunohistology - Paraffin | |||
Western Blotting |
- Flow Cytometry
- Use 10ul of the suggested working dilution to label 1x106 cells in 100ul.
- Western Blotting
- MCA2723 detects band/s of approximately 29-31kDa on fractionated cat lymphocyte cell lysates under non-reducing conditions.
Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
---|---|---|---|---|---|---|---|
Goat anti Mouse IgG (H/L):FITC (Multi Species Adsorbed) | STAR117F | F | 0.5 mg | Log in | |||
List Price | Your Price | ||||||
Log in | |||||||
Description | Goat anti Mouse IgG (H/L):FITC (Multi Species Adsorbed) | ||||||
Rabbit F(ab')2 anti Mouse IgG:RPE | STAR12A | F | 1 ml | Log in | |||
List Price | Your Price | ||||||
Log in | |||||||
Description | Rabbit F(ab')2 anti Mouse IgG:RPE | ||||||
Rabbit F(ab')2 anti Mouse IgG:HRP (Human Adsorbed) | STAR13B | C E P RE WB | 1 mg | Log in | |||
List Price | Your Price | ||||||
Log in | |||||||
Description | Rabbit F(ab')2 anti Mouse IgG:HRP (Human Adsorbed) | ||||||
Rabbit F(ab')2 anti Mouse IgG:FITC | STAR9B | F | 1 mg | Log in | |||
List Price | Your Price | ||||||
Log in | |||||||
Description | Rabbit F(ab')2 anti Mouse IgG:FITC |
Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
---|---|---|---|---|---|---|---|
Mouse IgG2b Negative Control | MCA691 | F | 100 Tests | Log in | |||
List Price | Your Price | ||||||
Log in | |||||||
Description | Mouse IgG2b Negative Control |
References for MHC Class II antibody
-
Hunt, P. et al. (1995) Variable expression of major histocompatibility complex class II in the domestic cat.
Res Vet Sci. 59 (3): 195-200. -
Lerner, D.L. et al. (1998) FIV infection of IL-2-dependent and -independent feline lymphocyte lines: host cells range distinctions and specific cytokine upregulation.
Vet Immunol Immunopathol. 65 (2-4): 277-97. -
Bradbury AM et al. (2017) AAV-mediated gene delivery attenuates neuroinflammation in feline Sandhoff disease.
Neuroscience. 340: 117-25.
- RRID
- AB_915359
MCA2723
158883 159895 161377 170914If you cannot find the batch/lot you are looking for please contact our technical support team for assistance.
Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
View all Anti-Cat ProductsAlways be the first to know.
When we launch new products and resources to help you achieve more in the lab.
Yes, sign me up