Browsing Modes for Business Users

IL-18BP antibody

Goat anti Mouse INTERLEUKIN-18BP:Preservative Free

Product Type
Polyclonal Antibody
Polyclonal IgG

Product Code Applications Pack Size List Price Your Price Qty
Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
E WB 0.1 mg loader
List Price Your Price

Goat anti Mouse interleukin-18BP antibody, recognizes interleukin-18-binidng protein (IL-18BP), also known as tadekinig-alpha. IL-18BP is a secreted immunoregulatory binding protein which binds to and inhibits the cytokine activity of mature IL-18 with high affinity. IL-18 plays a role in host defense, inflammation, tissue repair, and regeneration (Mühl & Bachmann 2019).

IL-18BP is constitutively expressed in the spleen, PBMCs, monocytes and umbilical vein endothelial cells (Mühl & Bachmann 2019, Corbaz et al. 2002). It is detectable in the serum of healthy humans at a 20 fold molar excess compared to IL-18, with subjects showing levels of 2,000 – 4,000 pg/ml of IL-18BP (Kaplanski et al. 2018). IL-18BP is upregulated in response to inflammation as part of the inflammation resolution process. Additionally, it can be upregulated during various cancers and IL-18BP levels are also affected by viral infections such as dengue and hepatitis C (Mühl & Bachmann 2019).

Target Species
Product Form
Purified IgG - lyophilized
Reconstitute with 0.1 ml distilled water
Antiserum Preparation
Produced from sera of goats immunized with recombinant mouse interleukin-18BP and purified by affinity chromatography
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
None present
Carrier Free
E. coli derived recombinant mouse interleukin-18BP
Approx. Protein Concentrations
IgG concentration 1.0 mg/ml after reconstitution
Endotoxin Level
< 0.1 ng/μg of protein (< 1 EU/μg)
For research purposes only
12 months from date of despatch

Prior to reconstitution store at -20°C.
After reconstitution store at -20°C.

This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
ELISA 0.5 ug/ml 2.0 ug/ml
Western Blotting 0.1 ug/ml 0.2 ug/ml
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.

Description Product Code Applications Pack Size List Price Your Price Quantity
Rabbit anti Goat IgG (Fc):FITC STAR122F F 1 mg loader
List Price Your Price
Description Rabbit anti Goat IgG (Fc):FITC
Rabbit anti Goat IgG (Fc):HRP STAR122P C E WB 1 mg loader
List Price Your Price
Description Rabbit anti Goat IgG (Fc):HRP

Entrez Gene
GO Terms
GO:0005576 extracellular region
GO:0042007 interleukin-18 binding
GO:0042088 T-helper 1 type immune response
GO:0048019 receptor antagonist activity



If you cannot find the batch/lot you are looking for please contact our technical support team for assistance.

View more products with IL-18 specificity

Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

View all Anti-Mouse Products
Please note