CDw198 antibody

Goat anti Mouse CDw198

Product Type
Polyclonal Antibody
Isotype
Polyclonal IgG
Specificity
CDw198

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AAM68
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SDS Safety Datasheet SDS
E P WB 0.1 mg loader
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Goat anti mouse CDw198 polyclonal antibody recognizes mouse CDw198, otherwise known as CCR8 (C-C chemokine receptor type 8), a transmembrane glycoprotein and member of the G-protein coupled receptor 1 family, which acts a high-affinity receptor for the chemokine I-309 (CCL1), implicated in the regulation of monocyte chemotaxis and thymocyte apoptosis.

CDw198 is constitutively expressed by monocytes, preferentially expressed on Th2 (type 2 helper T) cells, and acts as a co-receptor with CD4 for HIV1 infection.

Target Species
Mouse
Product Form
Purified IgG - liquid
Antiserum Preparation
Antiserum to mouse CDw198 was raised by repeated immunisation of goats with highly purified antigen. Purified IgG was prepared by affinity chromatography.
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.1% Sodium Azide (NaN3)
0.1% Bovine Serum Albumin
Immunogen
Synthetic peptide PNVTMTDYYPDFFTAPCDAEFLLRGSM corresponding to amino acids 7-33 of mouse CDw198.
Approx. Protein Concentrations
IgG concentration 1.0mg/ml
Regulatory
For research purposes only
Guarantee
12 months from date of despatch

Store at -20oC only.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
ELISA 1/100000
Immunohistology - Paraffin 1/400
Western Blotting 1/1000
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
ELISA
This product is suitable for use in indirect ELISA applications.
Histology Positive Control Tissue
Spleen

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Antigen Retrieval Buffer, pH8.0 BUF025A P 500 ml
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Synonyms
CCR8
RRID
AB_2073102
UniProt
P56484
Entrez Gene
Ccr8
GO Terms
GO:0005886 plasma membrane
GO:0016021 integral to membrane
GO:0006935 chemotaxis
GO:0016493 C-C chemokine receptor activity
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

View all Anti-Mouse Products