UTF1 antibody

Rabbit anti Human UTF1

Product Type
Polyclonal Antibody
Isotype
Polyclonal IgG
Specificity
UTF1

Product Code Applications Pack Size List Price Your Price Qty
AHP3112
Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
WB 0.1 ml loader
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loader
Search for Batch Specific Datasheets

Rabbit anti Human UTF1 antibody recognizes undifferentiated embryonic cell transcription factor 1.

UTF1 is a protein expressed in the nuclei of pluripotent cells such as embryonic stem cells and embryonic carcinoma cells where it regulates chromatin state and mRNA levels by promoting degradation of mRNA (Jia et al. 2012). Expression of UTF1 quickly reduces upon differentiation. UTF1 is overexpressed in cervical cancer cells (Guenin et al. 2012).

Target Species
Human
Species Cross-Reactivity
Target SpeciesCross Reactivity
Mouse
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Purified IgG - liquid
Antiserum Preparation
Antiserum to human UTF1 was raised by repeated immunization of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.035% Sodium Azide (NaN3)
30% Glycerol
Carrier Free
Yes
Immunogen
A peptide within the N-terminal region of human UTF1
Regulatory
For research purposes only
Guarantee
12 months from date of despatch

This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.

Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/500 1/1000
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.

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UniProt
Q5T230
Entrez Gene
UTF1
GO Terms
GO:0005515 protein binding
GO:0003702 RNA polymerase II transcription factor activity
GO:0003713 transcription coactivator activity
GO:0005634 nucleus
GO:0008584 male gonad development
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

View all Anti-Human Products