Tubulin Alpha 4A Chain antibody
Rabbit anti Human tubulin alpha 4A chain antibody recognizes tubulin alpha 4A chain, also known as tubulin H2-alpha, tubulin alpha-1 chain, and tubulin, alpha 1 (testis specific).
Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulin. The genes encoding these microtubule constituents are part of the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes and they are highly conserved among and between species. Encoded by the TUBA4A gene, tubulin alpha 4A chain is a highly conserved homolog of a rat testis-specific alpha tubulin. Alternatively spliced transcript variants encoding different isoforms have been found for TUBA4A (provided by RefSeq, Jun 2013).
Rabbit anti Human tubulin alpha 4A chain antibody detects a band of 55 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulin. The genes encoding these microtubule constituents are part of the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes and they are highly conserved among and between species. Encoded by the TUBA4A gene, tubulin alpha 4A chain is a highly conserved homolog of a rat testis-specific alpha tubulin. Alternatively spliced transcript variants encoding different isoforms have been found for TUBA4A (provided by RefSeq, Jun 2013).
Rabbit anti Human tubulin alpha 4A chain antibody detects a band of 55 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
Product Details
- Target Species
- Human
- Western Blotting
- Anti tubulin alpha 4A chain detects a band of approximately 55 kDa in HeLa cell lysates
- Species Cross-Reactivity
-
Target Species Cross Reactivity Mouse Rat - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Preparation
- Rabbit polyclonal antibody purified by affinity chromatography
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3)
- Immunogen
- KLH conjugated synthetic peptide between 417-446 amino acids from the C-terminal region of human tubulin alpha 4A chain
Storage Information
- Storage
- Store undiluted at -20oC, avoiding repeated freeze thaw cycles.
- Guarantee
- 12 months from date of despatch
More Information
- UniProt
- P68366
- Entrez Gene
- TUBA4A
- GO Terms
- GO:0000086 G2/M transition of mitotic cell cycle
- GO:0005515 protein binding
- GO:0003924 GTPase activity
- GO:0002576 platelet degranulation
- GO:0005576 extracellular region
- GO:0005829 cytosol
- GO:0005198 structural molecule activity
- GO:0005525 GTP binding
- GO:0005874 microtubule
- GO:0007018 microtubule-based movement
- GO:0030168 platelet activation
- GO:0051084 'de novo' posttranslational protein folding
- GO:0051258 protein polymerization
- Acknowledgements
- PrecisionAb is a trademark of Bio-Rad Laboratories.
- Regulatory
- For research purposes only
Applications of Tubulin Alpha 4A Chain antibody
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Western Blotting | 1/1000 |
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
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