Rabbit anti TRAF3 antibody recognizes TNF receptor-associated factor 3 (TRAF3) also known as CD40 receptor-associated factor 1, CAP-1 and LMP1-associated protein 1. TRAF3 belongs to the TNF receptor-associated factor (TRAF) family of proteins. TRAF3 is involved in the regulation of NF-kappa-B and MAP kinase activation, along with the regulation of B cell survival.
- Target Species
- Species Cross-Reactivity
|Target Species||Cross Reactivity|
- N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Antiserum Preparation
- Antiserum to TRAF3 was raised by repeated immunization of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.02% Sodium Azide
- Synthetic human TRAF3 peptide
- Store at -20oC
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
- 12 months from date of despatch
- Entrez Gene
- GO Terms
toll-like receptor signaling pathway
ubiquitin-protein ligase activity
signal transducer activity
induction of apoptosis
zinc ion binding
internal side of plasma membrane
regulation of proteolysis
negative regulation of NF-kappaB transcription factor activity
negative regulation of type I interferon production
regulation of interferon-beta production
tumor necrosis factor-mediated signaling pathway
CD40 receptor complex
regulation of defense response to virus
- For research purposes only
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Applications of TRAF3 antibody
|Immunohistology - Paraffin
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
- Western Blotting
- Rabbit anti TRAF3 antibody detects a band of approximately 64 kDa in cell lysates and tissue lysates under reducing conditions
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Secondary Antibodies Available
Useful Reagents Available