TRAF3 antibody

Rabbit anti TRAF3

Product Type
Polyclonal Antibody
Isotype
Polyclonal IgG
Specificity
TRAF3

Product Code Applications Pack Size List Price Your Price Qty
AHP2535
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SDS Safety Datasheet SDS
IF P WB 50 µl loader
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Rabbit anti TRAF3 antibody recognizes TNF receptor-associated factor 3 (TRAF3) also known as CD40 receptor-associated factor 1, CAP-1 and LMP1-associated protein 1. TRAF3 belongs to the TNF receptor-associated factor (TRAF) family of proteins. TRAF3 is involved in the regulation of NF-kappa-B and MAP kinase activation, along with the regulation of B cell survival.

Target Species
Human
Species Cross-Reactivity
Target SpeciesCross Reactivity
Mouse
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Purified IgG - liquid
Antiserum Preparation
Antiserum to TRAF3 was raised by repeated immunization of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.02% Sodium Azide
50% Glycerol
Immunogen
Synthetic human TRAF3 peptide
Regulatory
For research purposes only
Guarantee
12 months from date of despatch

Store at -20oC
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Immunofluorescence 1/50 1/200
Immunohistology - Paraffin 1/50 1/200
Western Blotting 1/200 1/1000
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
Western Blotting
Rabbit anti TRAF3 antibody detects a band of approximately 64 kDa in cell lysates and tissue lysates under reducing conditions

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UniProt
Q13114
Entrez Gene
TRAF3
GO Terms
GO:0005515 protein binding
GO:0002224 toll-like receptor signaling pathway
GO:0006915 apoptosis
GO:0005739 mitochondrion
GO:0005829 cytosol
GO:0004842 ubiquitin-protein ligase activity
GO:0004871 signal transducer activity
GO:0005768 endosome
GO:0006917 induction of apoptosis
GO:0008270 zinc ion binding
GO:0009898 internal side of plasma membrane
GO:0030162 regulation of proteolysis
GO:0032088 negative regulation of NF-kappaB transcription factor activity
GO:0032480 negative regulation of type I interferon production
GO:0032648 regulation of interferon-beta production
GO:0033209 tumor necrosis factor-mediated signaling pathway
GO:0035631 CD40 receptor complex
GO:0050688 regulation of defense response to virus
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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