SLPI antibody

Rabbit anti SLPI

Product Type
Polyclonal Antibody
Isotype
Polyclonal IgG
Specificity
SLPI

Product Code Applications Pack Size List Price Your Price Qty
AHP1437
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SDS Safety Datasheet SDS
P * WB 0.1 mg loader
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Rabbit anti Human SLPI antibody recognizes secretory leukocyte protease inhibitor (SLPI), a ~14 kDa non-glycosylated protein produced by secretory cells in the respiratory, genital and lachrymal glands, and by macrophages, B-cells and neutrophils.

The functions of SLPI are diverse. The SLPI protein inhibits protease activity at sites of inflammation, protecting tissues against protease mediated damage and it possesses anti-microbial/anti-viral activity. In addition, SLPI has been reported to exhibit anti-inflammatory properties, regulating lipopolysaccharide induced activation of NF-kappa beta in peripheral blood monocytes.

Target Species
Human
Species Cross-Reactivity
Target SpeciesCross Reactivity
Mouse
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Purified IgG - liquid
Antiserum Preparation
Antisera to human SLPI were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared by affinity chromatography.
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.02%Sodium Azide
Immunogen
A 17 amino acid peptide located near the centre of human SLPI.
Approx. Protein Concentrations
IgG concentration 1.0 mg/ml
Regulatory
For research purposes only
Guarantee
12 months from date of despatch

This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.

Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Immunohistology - Paraffin 1
Western Blotting 1.0 2.0ug/ml
  1. 1This product requires antigen retrieval using heat treatment prior to staining of paraffin sections. Sodium citrate buffer pH 6.0 is recommended for this purpose.
Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
Western Blotting
AHP1437 detects a band of approximately 14kDa in Daudi cell lysates.

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Synonyms
HUSI-1
RRID
AB_2195061
UniProt
P03973
Entrez Gene
SLPI
GO Terms
GO:0005576 extracellular region
GO:0004867 serine-type endopeptidase inhibitor activity
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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