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PRKAR1A antibody

Rabbit anti PRKAR1A

Product Type
Polyclonal Antibody
Isotype
Polyclonal IgG
Specificity
PRKAR1A

Product Code Applications Pack Size List Price Your Price Qty
AHP2514
Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
P WB 50 µl loader
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Rabbit anti PRKAR1A antibody recognizes PRKAR1A also known as cAMP-dependent protein kinase type I-alpha regulatory subunit. PRKAR1A is an inhibitory subunit of cAMP-dependent kinase which dissociates upon binding of cAMP.

Target Species
Human
Species Cross-Reactivity
Target SpeciesCross Reactivity
Mouse
Rat Expected from Sequence
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Purified IgG - liquid
Antiserum Preparation
Antiserum to PRKAR1A was raised by repeated immunization of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.02% Sodium Azide
50% Glycerol
Immunogen
Recombinant human PRKAR1A
Regulatory
For research purposes only
Guarantee
12 months from date of despatch

Store at -20oC
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Immunohistology - Paraffin 1/50 1/200
Western Blotting 1/500 1/2000
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
Western Blotting
Rabbit anti PRKAR1A antibody detects a band of approximately 43 kDa in cell lysates and tissue lysates under reducing conditions

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UniProt
P10644
Entrez Gene
PRKAR1A
GO Terms
GO:0005515 protein binding
GO:0001932 regulation of protein phosphorylation
GO:0007596 blood coagulation
GO:0005829 cytosol
GO:0035556 intracellular signal transduction
GO:0005952 cAMP-dependent protein kinase complex
GO:0006112 energy reserve metabolic process
GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0006833 water transport
GO:0007202 activation of phospholipase C activity
GO:0050796 regulation of insulin secretion
GO:0008603 cAMP-dependent protein kinase regulator activity
GO:0030552 cAMP binding
GO:0034199 activation of protein kinase A activity
GO:0048011 nerve growth factor receptor signaling pathway
GO:0055085 transmembrane transport
GO:0071377 cellular response to glucagon stimulus

AHP2514

141478 167648 168526

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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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