PPM1D antibody

Rabbit anti Human PPM1D

Product Type
Polyclonal Antibody
Isotype
Polyclonal IgG
Specificity
PPM1D

Product Code Applications Pack Size List Price Your Price Qty
AHP3097
Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
WB 0.1 ml loader
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loader
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Rabbit anti Human PPM1D antibody recognizes protein phosphatase 1D, also known as histone-arginine N-methyltransferase PRMT2.

PPM1D is an enzyme that functions as a member of the PP2C family of Ser/Thr protein phosphatases. PP2C Ser/Thr protein phosphatases have been shown to inhibit cell stress response pathways. Aberrant levels of PPM1D expression have also been observed in some breast cancers (Deng et al. 2020).

Target Species
Human
Product Form
Purified IgG - liquid
Antiserum Preparation
Antiserum to human PPM1D was raised by repeated immunization of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.035% Sodium Azide (NaN3)
30% Glycerol
Carrier Free
Yes
Immunogen
A peptide within the C-terminal region of human PPM1D
Regulatory
For research purposes only
Guarantee
12 months from date of despatch

This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.

Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/250 1/500
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.

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UniProt
O15297
Entrez Gene
PPM1D
GO Terms
GO:0005515 protein binding
GO:0004722 protein serine/threonine phosphatase activity
GO:0046872 metal ion binding
GO:0005634 nucleus
GO:0006470 protein dephosphorylation
GO:0008285 negative regulation of cell proliferation
GO:0008287 protein serine/threonine phosphatase complex
GO:0009314 response to radiation
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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