PAX6 antibody

Rabbit anti Human PAX6

Product Type
Polyclonal Antibody
Isotype
Polyclonal IgG
Specificity
PAX6

Product Code Applications Pack Size List Price Your Price Qty
AHP3092
Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
WB 0.1 ml loader
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loader
Search for Batch Specific Datasheets

Rabbit anti Human PAX6 antibody recognizes paired box protein PAX6, also known as aniridia type II protein (AN2) or oculorhombin.

PAX proteins contain a highly conserved DNA-binding domain, known as the paired box, and are important in the early stages of development. PAX6 expression has been shown to be particularly important for the development of eyes and other sensory organs as well as certain neural and epidermal tissues (Fernald, 2004).

Target Species
Human
Product Form
Purified IgG - liquid
Antiserum Preparation
Antiserum to human PAX6 was raised by repeated immunization of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.035% Sodium Azide (NaN3)
30% Glycerol
Carrier Free
Yes
Immunogen
A peptide within the C-terminal region of human PAX6
Regulatory
For research purposes only
Guarantee
12 months from date of despatch

This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.

Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/500 1/1000
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.

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UniProt
P26367
Entrez Gene
PAX6
GO Terms
GO:0005515 protein binding
GO:0001654 eye development
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0004842 ubiquitin-protein ligase activity
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0006355 regulation of transcription, DNA-dependent
GO:0009887 organ morphogenesis
GO:0007417 central nervous system development
GO:0007601 visual perception
GO:0009611 response to wounding
GO:0030528 transcription regulator activity
GO:0043565 sequence-specific DNA binding
GO:0048663 neuron fate commitment
GO:0050768 negative regulation of neurogenesis
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

View all Anti-Human Products