OGA antibody

Rabbit anti Human OGA

Product Type
Polyclonal Antibody
Isotype
Polyclonal IgG
Specificity
OGA

Product Code Applications Pack Size List Price Your Price Qty
AHP3090
Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
IP WB 0.1 ml loader
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loader
Search for Batch Specific Datasheets

Rabbit anti Human OGA antibody recognizes OGA (O-GlcNAcase), also known as glycoside hydrolase, BtGH84 or O-GlcNAc hydrolase.

OGA catalyses the removal of O-GlcNAc post-translational modifications; a reversible enzymatic post-translational modification characterized by a β-glycosidic bond between the hydroxyl group of serine or threonine side chains and N-acetylglucosamine (GlcNAc) Removal of O-GlcNAc from proteins like tau and the β-amyloid protein has been linked neurological disorders (Wells et al. 2002).

Target Species
Human
Product Form
Purified IgG - liquid
Antiserum Preparation
Antiserum to human OGA was raised by repeated immunization of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.035% Sodium Azide (NaN3)
30% Glycerol
Carrier Free
Yes
Immunogen
A peptide within the N-terminal region of human OGA
Regulatory
For research purposes only
Guarantee
12 months from date of despatch

This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.

Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Immunoprecipitation 10 µl per IP
Western Blotting 1/500 1/2000
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.

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UniProt
O60502
Entrez Gene
MGEA5
GO Terms
GO:0004402 histone acetyltransferase activity
GO:0004415 hyalurononglucosaminidase activity
GO:0004563 beta-N-acetylhexosaminidase activity
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0006516 glycoprotein catabolic process
Request a different product with this specificity

Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

View all Anti-Human Products