NFATC2 antibody

Rabbit anti Human NFATC2

Product Type
Polyclonal Antibody
Isotype
Polyclonal IgG
Specificity
NFATC2

Product Code Applications Pack Size List Price Your Price Qty
AHP3087
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SDS Safety Datasheet SDS
IP WB 0.1 ml loader
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Rabbit anti Human NFATC2 antibody recognizes nuclear factor of activated T-cells, cytoplasmic 2.

NFATC2 is a 100 kDa member of the nuclear factor of activated T cells (NFAT) family normally located to the cytosol. However, upon T cell receptor (TCR) stimulation NFATC2 is translocated to the nucleus where it becomes a member of the Nuclear factors of activated T cells transcription complex. The T cells transcription complex plays a vital role in inducing gene transcription during the immune response (Rao et al. 1997).

Target Species
Human
Product Form
Purified IgG - liquid
Antiserum Preparation
Antiserum to human NFATC2 was raised by repeated immunization of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.035% Sodium Azide (NaN3)
30% Glycerol
Carrier Free
Yes
Immunogen
A peptide within the N-terminal region of human NFATC2
Regulatory
For research purposes only
Guarantee
12 months from date of despatch

This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.

Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Immunoprecipitation 10 µl per IP
Western Blotting 1/500 1/2000
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.

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UniProt
Q13469
Entrez Gene
NFATC2
GO Terms
GO:0005886 plasma membrane
GO:0005515 protein binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005634 nucleus
GO:0006974 response to DNA damage stimulus
GO:0042493 response to drug
GO:0015629 actin cytoskeleton
GO:0016563 transcription activator activity
GO:0030890 positive regulation of B cell proliferation
GO:0050853 B cell receptor signaling pathway
GO:0071109 superior temporal gyrus development
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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