LXR-beta antibody

Rabbit anti Human LXR-beta

Product Type
Polyclonal Antibody
Isotype
Polyclonal IgG
Specificity
LXR-beta

Product Code Applications Pack Size List Price Your Price Qty
AHP3083
Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
Ch WB 0.1 ml loader
List Price Your Price
loader
Search for Batch Specific Datasheets

Rabbit anti Human LXR-beta antibody recognizes oxysterols receptor LXR-beta, also known as liver X receptor beta.

LXR-beta is a member of the nuclear receptor family of transcription factors. As with other members of this family of transcription factors, LXR-beta heterodimerizes with retinoid X receptor and specifically binds to response elements known as LXREs (Song et al. 1995).

Target Species
Human
Product Form
Purified IgG - liquid
Antiserum Preparation
Antiserum to human LXR-beta was raised by repeated immunization of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.035% Sodium Azide (NaN3)
30% Glycerol
Carrier Free
Yes
Immunogen
A peptide in the N-terminal region of human LXR-beta
Regulatory
For research purposes only
Guarantee
12 months from date of despatch

This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.

Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Chromatin Immunoprecipitation 10 µl per ChIP
Western Blotting 1/500 1/1000
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.

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UniProt
P55055
Entrez Gene
NR1H2
GO Terms
GO:0003707 steroid hormone receptor activity
GO:0005737 cytoplasm
GO:0005654 nucleoplasm
GO:0008270 zinc ion binding
GO:0010552 positive regulation of gene-specific transcription from RNA polymerase II promoter
GO:0010745 negative regulation of macrophage derived foam cell differentiation
GO:0010867 positive regulation of triglyceride biosynthetic process
GO:0010875 positive regulation of cholesterol efflux
GO:0010887 negative regulation of cholesterol storage
GO:0032270 positive regulation of cellular protein metabolic process
GO:0032369 negative regulation of lipid transport
GO:0034339 regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor
GO:0043565 sequence-specific DNA binding
GO:0045723 positive regulation of fatty acid biosynthetic process
GO:0048550 negative regulation of pinocytosis
GO:0051006 positive regulation of lipoprotein lipase activity
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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