KMT2E antibody
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WB ResetRabbit anti Human KMT2E
- Product Type
- Polyclonal Antibody
- Isotype
- Polyclonal IgG
- Specificity
- KMT2E
Antibody Quality and Performance Guarantee
| Rabbit anti Human KMT2E antibody recognizes lysine methyltransferase 2E, otherwise known as MLL5. KMT2E is a member of the myeloid/lymphoid or mixed-lineage leukemia (MLL) family of proteins, a group of proteins that are homologous to the evolutionary conserved trithorax group crucial for the regulation of homeotic gene (HOX) expression and embryonic development (Zhang et al. 2017). Aberrant levels of KMT2E have been shown to inhibit cell cycle progression. Mutations in the KMT2E gene have also been associated with neurological disorders such epilepsy and autism as well as abnormalities in gastrointestinal function (O’Donnell-Luria et al. 2019). |
- Target Species
- Human
- Species Cross-Reactivity
-
Target Species Cross Reactivity Mouse - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Antiserum Preparation
- Antiserum to human KMT2E was raised by repeated immunization of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.035% Sodium Azide (NaN3)
30% Glycerol - Carrier Free
- Yes
- Immunogen
- A peptide within human KMT2E
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Western Blotting |  |
1/500 | 1/2000 |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
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AHP3082
160772
If you cannot find the batch/lot you are looking for please contact our technical support team for assistance.
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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